ReviewEndocrine reviews2025
Obesity and Exercise: New Insights and Perspectives.
Review in Endocrine reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of nutritional supplementation combined with exercise on BMI and lipid profiles in individuals with overweight or obesity: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Exercise-induced changes in systemic inflammatory biomarkers in overweight and obese populations: a bibliometric analysis and umbrella review of meta-analyses.Frontiers in immunology · 2026Pooled it
- Global landscape of liver disease burden in 1990-2021.iScience · 2026Article
- Physical exercise and miR-146a in type 2 diabetes and obesity: a narrative review.Molecular biology reports · 2026Review
- The long non-coding RNA landscape of endurance exercise training.Molecular metabolism · 2026Article
- Exercise-Induced Myokines in Obesity-Related Metabolic Disorders and Cardiovascular Protection: A Narrative Review.Sports (Basel, Switzerland) · 2026Review
- Circadian Reprogramming by Combined Time-Restricted Feeding and Exercise Improves Metabolic Homeostasis in Diabetes.Metabolites · 2026Article
- Extracellular Vesicles in Obesity: From Pathophysiological Mediators to Therapeutic Tools.International journal of molecular sciences · 2026Review
- Obesity is the culprit behind fatty acid-induced inflammation.Nutrition & metabolism · 2026Review
- A new form of diabetes caused by INS mutations defined by zygosity, stem cell and population data.EMBO molecular medicine · 2026Article
- Article
- Global, Regional, and Future Predictions of Cardiovascular Disease Burden Among Women of Childbearing Age: A Systematic Analysis of the Global Burden of Disease Study 1990-2021.International journal of women's health · 2026Article
- Sarcopenia and sepsis fuel a self-perpetuating cycle of immunometabolism decline.Frontiers in immunology · 2026Review
- Association of accelerometer-measured physical activity and the risk of incident cardiovascular diseases within the AHA cardiovascular-kidney-metabolic syndrome 0-4 framework: a prospective cohort of the UK Biobank.Frontiers in endocrinology · 2026Article
- The Long Non-coding RNA Landscape of Endurance Exercise Training.bioRxiv : the preprint server for biology · 2025Article
- Visceral fat area loss reduces 10-year atherosclerotic cardiovascular disease risk in Chinese population with type 2 diabetes mellitus: a prospective cohort study.Lipids in health and disease · 2025Article
- Synergistic effects of polyphenols and exercise on obesity: targeting metabolism, muscle function, and adipose tissue remodeling.Frontiers in nutrition · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Obesity is increasing rapidly worldwide and is projected to affect approximately half the US population by the year 2035. Obesity is a complex condition, and individuals who have obesity are at greater risk for developing associated metabolic diseases such as type 2 diabetes (T2D), metabolic dysfunction-associated steatohepatitis (MASH), and cardiovascular diseases (CVD). Understanding the underlying factors which contribute to obesity and that impact key molecular mechanisms of metabolic organs such as adipose tissue, liver, and muscle is crucial for combating the disease. Exercise is a well-established measure to prevent or mitigate the adverse consequences of obesity, with several beneficial effects to whole-body metabolism and adaptations to metabolic tissues. This review explores the impact of obesity on the development of metabolic diseases. Specifically, we will discuss: how obesity alters metabolic function and the potential benefits of exercise; the specific effects of obesity and exercise on muscle, adipose tissue, and liver; and potential effects of pharmacotherapeutics or bariatric surgery in combination with exercise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.