Evidence map›Paper›PMID 40522658›Full record

ArticleJAMA network open2025

Clinicians' Perceptions About Institutional Factors in Moral Distress Related to Potentially Nonbeneficial Treatments.

Teva D Brender, Julia K Axelrod, Sofia Weiss Goitiandia, Jason N Batten, Elizabeth W Dzeng

Abstract read
In one paragraph

Article in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Teva D BrenderDepartment of Medicine, University of California, San Francisco.
Julia K AxelrodDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco.
Sofia Weiss GoitiandiaDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco.
Jason N BattenDivision of Cardiothoracic Anesthesiology, Department of Anesthesiology and Perioperative Medicine, University of California, Los Angeles.
Elizabeth W DzengDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco.

Funding

Identifying opportunities to improve shared decision-making about intensity of care for patients with Alzheimer's disease and related dementiasR01NR018161 · NINR · UNIVERSITY OF WASHINGTON · PI CREUTZFELDT, CLAIRE JOHANNA, ENGELBERG, RUTH ANN · 2018 to 2022
$3.7M
Understanding and Addressing Systemic Factors Influencing the Quality of End-of-Life Care in Older AdultsK76AG074906 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Elizabeth Dzeng · 2022 to 2026
$1.1M
NIA NIH HHS K76 AG074906NINR NIH HHS R01 NR018161
6 · The paper itself

Abstract

Importance: Clinicians commonly experience moral distress related to potentially nonbeneficial life-sustaining treatments (LST). Hospitals' institutional culture (eg, shared beliefs, values, and practices), structures (eg, policies, practices, resource allocation), and societal-level factors (eg, national culture, local and national policies, medical hierarchies) may contribute to moral distress related to potentially nonbeneficial LST. Objective: To investigate clinicians' perspectives on how hospitals' institutional culture and structures might exacerbate, prevent, or mitigate the influence of societal factors contributing to moral distress related to potentially nonbeneficial LST. Design, Setting, and Participants: This qualitative study used comparative ethnographic methods. Semistructured, in-depth interviews were conducted between February 2018 and June 2022 at 4 West Coast academic hospitals selected for their varying intensities of end-of-life care. Interview participants were hospital-based clinicians (eg, nurses, physicians), hospital leaders (eg, unit nursing and medical directors), and administrators with differing clinical backgrounds and professional responsibilities. Data were analyzed in 2 phases, from January 2019 to December 2022 and from June to September 2024. Main Outcomes and Measures: Clinicians were asked about their hospitals' institutional culture and structures and their relationship to clinicians' experiences of moral distress related to potentially nonbeneficial LST in end-of-life care. Results: A total of 122 interviews were conducted (75 physicians [61%]; 22 nurses [18%]; 6 advanced practice clinicians [6%]; 68 [56%] women; mean [range] age, 42 [27-74] years). Respondents felt hospitals' institutional culture and structures could exacerbate moral distress. Respondents reported that a hospital culture of health care consumerism influenced clinicians', patients', and families' expectations for treatment intensity, contributing to morally distressing situations. Nurses and primary team physicians felt constrained by medical hierarchies, leading to perceptions of disempowerment and moral distress. Clinicians also reported that institutions lacked sufficient structures to support efforts to de-escalate potentially nonbeneficial treatments. However, respondents also reported that hospitals' institutional culture and structures could prevent or mitigate moral distress. Respondents felt policies empowering clinicians across the medical hierarchy to participate in decision-making reduced moral distress. They reported that institutional resources could manage conflicts and provide emotional support when moral distress occurs. Furthermore, respondents felt that clinician-driven quality improvement initiatives and supportive hospital leaders could address hospitals' institutional cultural and structural contributors to moral distress. Conclusions and Relevance: In this qualitative study, clinicians perceived that institutional factors affected their experiences of moral distress related to potentially nonbeneficial LST by exacerbating, preventing, or mitigating the influence of 3 societal factors: defaults of high-intensity treatments, health care consumerism, and medical hierarchies. These results have implications for developing tailored institutional-level interventions to address societal and institutional contributors to moral distress from potentially nonbeneficial LST.

Indexed as

Attitude of Health PersonnelMoralsOrganizational CultureTerminal CareAdultEthical DilemmasFemaleHumansMaleMiddle AgedQualitative Research

Identifiers

PMID40522658
PMCPMC12171942

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.