Evidence map›Paper›PMID 40522609›Full record

ArticleSports medicine (Auckland, N.Z.)2025

Health and Performance Challenges in the Era of Human Enhancement: Insights from Sport Medicine Professionals.

Ke Hu, Christian Schneider, Mark R Hutchinson, Emin Ergen, Michael Geistlinger, Iain Killoughery, Klaus-Michael Braumann, José Kawazoe Lazzoli, Jane Seto, Xavier Bigard and 51 more

Abstract read
In one paragraph

Article in Sports medicine (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

61 authors.

Ke HuDepartment of Sports and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China.
Christian SchneiderOrthopaedic Centre Theresie, Munich, Germany.
Mark R HutchinsonOrthopaedics and Sports Medicine, University of Illinois at Chicago, Chicago, USA.
Emin ErgenGloria Sports Arena, Sports Medicine Unit, Belek, Antalya, Turkey.
Michael GeistlingerDepartment of International and European Law and Fundaments of Law, University of Salzburg, Salzburg, Austria.
Iain KillougheryDepartment of Sports and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China.
Klaus-Michael BraumannDepartment of Sport and Exercise Medicine, Faculty of Psychology and Human Movement Science, University of Hamburg, Hamburg, Germany.
José Kawazoe LazzoliBiomedical Institute, Fluminense Federal University Medical School, Niterói, Brazil.
Jane SetoMurdoch Children's Research Institute, Parkville, Australia.
Xavier BigardUnion Cycliste Internationale, Aigle, Switzerland.
André DebruyneEuropean Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.
Anna JegierEuropean Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.
Theodora PapadopoulouEuropean Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.
Pedro ManonellesEuropean Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.
Francisco ArroyoSport Med, Fédération Internationale de Football Association (FIFA) Medical Centre of Excellence, Zapopan, Jalisco, Mexico.
Mourad GhrairiDepartment of Sports Medicine, FIFA Medical Centre of Excellence, Dubai, United Arab Emirates.
Ana V CintrónEuropean Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.
Petra ZupetInstitute for Medicine and Sports (IMŠ), Ljubljana, Slovenia.
Marcelo Bichels LeitãoInstituto de Endocrinologia E Medicina Do Exercico, Curitiba, Brazil.
Umutcan KayikciDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynaecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Daniel Arkader KopileCardiac Rehabilitation Department, National Institute of Cardiology, Health Ministry, Laranjeiras, Brazil.
Fabio PigozziDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Rome, Italy.
Chiara FossatiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Rome, Italy.
Alessia Di GianfrancescoDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Rome, Italy.
Luigi Di LuigiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Rome, Italy.
Kirill Micallef StafraceMater Dei Hospital Malta, Triagon Academy, Marsa, Malta.
Anca IonescuEuropean Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.
Bernd WolfarthUniversität Berlin and Humboldt-Universität, Berlin, Germany.
Metin ErgünTurkish Sports Medicine Association, Izmir, Türkiye.
William O RobertsDepartment of Family Medicine and Community Health, University of Minnesota, Minneapolis, United States of America.
Konstantinos NatsisDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Camille ToothPhysical Medicine and Rehabilitation, University Hospital of Liege, University of Liege, Liege, Belgium.
Sandra RozenštokaRiga Stradins University, Riga, Latvia.
José Antonio CasajúsPhysiopathology of Obesity and Nutrition Networking Biomedical Research Centre (CIBEROBN), Carlos III Health Institute, Madrid, Spain.
Borja Muniz-PardosGrowth, Exercise, Nutrition and Development (EXER-GENUD) Research Group, Faculty of Health and Sport Sciences, University of Zaragoza, Zaragoza, Spain.
Roberto Lohn NahonTitular Member of the Brazilian Society of Exercise and Sports Medicine (SBME), São Paulo, Brazil.
Malav ShroffWorld Olympians Association, Lausanne, Switzerland.
Minhao XieChina National Institute of Sports Medicine (NISM) Sports Medicine Hospital of NISM, Beijing, China.
Demitri ConstantinouDepartment of Exercise Science and Sports Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Dina CJanse van RensburgSouth African Sports Medicine Association (SASMA), Pretoria, South Africa.
Bülent ÜlkarDepartment of Sports Medicine, Faculty of Medicine, Ankara University, Ankara, Turkey.
Andrew JowettOlympic Park Sports Medicine Centre, Melbourne, Australia.
Victoriya BadtievaSport Medicine, I M Sechenov First Moscow State Medical University, Moscow, Russia.
Jean-François KauxPhysical Medicine and Rehabilitation, University Hospital of Liege, University of Liege, Liege, Belgium.
Peter BaumgartlAustrian Society of Sports Medicine and Prevention, Vienna, Austria.
Clea Hadjistephanou PapaellinaDepartment of Education, University of Cyprus, Nicosia, Cyprus.
Jürgen SteinackerInstitute of Rehabilitation Medicine Research, Ulm University, Ulm, Germany.
Julio Motta-PensabeneSportsMed Clinic Universidad de San Carlos de Guatemala, Guatemala City, Guatemala.
Rüdiger ReerDepartment of Sport and Exercise Medicine, Faculty of Psychology and Human Movement Science, University of Hamburg, Hamburg, Germany.
Norbert BachlAustrian Institute of Sports Medicine, Vienna, Austria.
Sergio MiglioriniMedical Committee, World Triathlon (WT), Lausanne, Switzerland.
Maher ZaharTunisian Centre of Sports Medicine and Science, Oral Health Unit, Tunis, Tunisia.
Mark StuartCentre for Metabolism and Inflammation, Division of Medicine, University College London, London, United Kingdom.
James BilzonDepartment for Health, University of Bath, Bath, United Kingdom.
Giuseppe MassazzaDivision of Physical Medicine and Rehabilitation, Department of Surgical Sciences, University of Turin, Turin, Italy.
Bruno Di PietroSapienza University of Rome, Rome, Italy.
Khaled Massoud HassanEgyptian Ministry of Youth and Sports, Mohandeseen, Giza, Egypt.
Felix Albuquerque DrummondInstituto de Medicina do Esporte (IME), Porto Alegre/Sports Medicine Institute, Porto Alegre, Brazil.
Bertrand FincoeurCollege of Humanities, Swiss Federal Technology Institute of Lausanne (EPFL), Lausanne, Switzerland.
Andrea PetrócziFaculty of Health and Sport Sciences, Széchenyi István University, Győr, Hungary.
Yannis PitsiladisDepartment of Sports and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China. ypitsiladis@hkbu.edu.hk.ORCID 0000-0001-6210-2449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the pursuit of sporting success, some elite athletes prioritise peak performance over long-term health, frequently resulting in significant and enduring health consequences. The Enhanced Games (TEG) position themselves as a bold experiment in transhumanism, advocating for the use of performance-enhancing drugs (PEDs), including methods banned by World Anti-Doping Agency (WADA), to push the boundaries of human athletic potential.

objectivesThe aim of this study is to explore the perspectives of sport physicians, sport scientists, physiotherapists and other allied healthcare professionals on treating and supporting "enhanced athletes", with the view of informing future guidelines.

methodsParticipants were invited via email and personal contacts within sport medicine communities to complete a brief anonymous survey via QuestionPro™. Descriptive statistics were performed using Excel™ and RStudio™.

resultsA total of 323 healthcare professionals responded (82% were sport physicians), among whom 74% expressed a willingness to treat acute lesions and/or chronic diseases in "enhanced athletes". In comparison, a considerable minority (30%) expressed support for assisting athletes in their use of PEDs and methods under medically supervised conditions, with high consistency across professional roles. A relatively high readiness was observed in sport physicians treating acute (77% versus 58%; p < 0.01) and chronic (75% versus 63%; p = 0.11) diseases for "enhanced athletes". As far as WADA rules and/or national anti-doping laws apply, this support presupposes compliance with the code and the respective national laws to protect physicians from serious professional, legal and personal consequences.

conclusionThe preliminary findings align with the broader goal of fostering a sport culture that values both peak performance and the short- and long-term health of all participants. These results emphasise the necessity of implementing professional guidelines and comprehensive support systems designed to safeguard the long-term well-being of all athletes and underscore the urgent need for further research into the impact of TEG on sport and its community.

Indexed as

Athletic PerformanceAttitude of Health PersonnelDoping in SportsSports MedicineAllied Health PersonnelAthletesFemaleHumansMalePerformance-Enhancing SubstancesPhysical TherapistsPhysiciansPractice Guidelines as TopicSelf ReportSurveys and QuestionnairesPerformance-Enhancing Substances

Identifiers

PMID40522609
PMCPMC12513872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.