Evidence map›Paper›PMID 40522581›Full record

ArticleJournal of medical ultrasonics (2001)2025

Changes in proximal colon on intestinal ultrasound indicate the efficacy of induction therapy for active ulcerative colitis.

Koichi Izumikawa, Tomoki Inaba, Eriko Yasutomi, Sakuma Takahashi, Hugh Shunsuke Colvin, Ichiro Sakakihara, Kumiko Yamamoto, Shigetomi Tanaka, Shigenao Ishikawa, Masaki Wato

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In one paragraph

Article in Journal of medical ultrasonics (2001), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Koichi IzumikawaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan. k_izumikawa2002@yahoo.co.jp.ORCID http://orcid.org/0000-0002-2465-117X
Tomoki InabaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Eriko YasutomiDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Sakuma TakahashiDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Hugh Shunsuke ColvinDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Ichiro SakakiharaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Kumiko YamamotoDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Shigetomi TanakaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Shigenao IshikawaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.
Masaki WatoDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahi-machi, Takamatsu, 760-8557, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to elucidate the effectiveness of intestinal ultrasound (IUS) in assessing induction therapy for active ulcerative colitis (UC).

methodsThirty-two patients (12 with severe colitis and 20 with moderate colitis) were analyzed. Disease activity was assessed using the Mayo endoscopic score (MES) obtained via colonoscopy. Ultrasound (US) grade and bowel wall thickness (BWT) before induction therapy were compared in terms of MES. Changes in US grade and BWT from pre-treatment to clinical improvement were analyzed at the most inflamed segments, oral side, and anal side.

resultsA correlation coefficient of 0.58 (p < 0.01) indicated a strong correlation between US grade and MES. US grade and BWT decreased at the most inflamed segments, oral side, and anal side for clinical improvement in all cases (p < 0.01, p < 0.01, respectively). However, changes in US grade were significantly greater on the oral side than the most inflamed segments or the anal side (p = 0.008 and p = 0.039, respectively).

conclusionIUS is an effective method for assessing the efficacy of induction therapy for active UC. The assessment should be performed at the proximal part of the colon, rather than solely at the site of the most pronounced inflammation.

Indexed as

Colitis, UlcerativeColonAdultAgedColonoscopyFemaleHumansInduction ChemotherapyMaleMiddle AgedTreatment OutcomeUltrasonographyYoung AdultColitisColonoscopyInduction therapyUlcerativeUltrasonography

Identifiers

PMID40522581
PMCPMC13021813

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.