Evidence map›Paper›PMID 40522544›Full record

ArticleMikrochimica acta2025

One-pot green synthesis of protein-modified ternary quantum dots.

Yueyue Zhang, Huixin Hou, Mengting Cao, Yiyang Zheng, Baozhu Wang, Yuan Zhou, Hang Qi, Zhijun Zhang, Yong-Miao Shen

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yueyue Zhang *Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Huixin Hou *Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Mengting CaoKey Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Yiyang ZhengKey Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Baozhu WangKey Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Yuan ZhouDepartment of Pharmacy, Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem Cells, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Hang QiShengzhou Innovation Research Institute of Zhejiang Sci-Tech University, Shengzhou, 312400, China. 52709326@qq.com.
Zhijun ZhangKey Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China. zjzhang@zstu.edu.cn.
Yong-Miao ShenKey Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China. shenym@zstu.edu.cn.

Funding

Shaoxing Industry-University-Research Collaborative Research and Development Project 2024B43005the Fundamental Research Funds of Shengzhou Innovation Research Institute of Zhejiang Sci-Tech University SYY2024B000004the Fundamental Research Funds of Zhejiang Sci-Tech University 24262132-YWenzhou Major Science and Technology Innovation Project ZZN2023002
6 · The paper itself

Abstract

In order to improve the stability, biocompatibility, and emissions of aqueous I-III-VI ternary quantum dots (QDs we report for the first time the one-pot two-step green synthesis method with proteins serving as modifier. As a proof of concept, bovine serum albumin (BSA) and lysozyme (Lys) modified CuInS@ZnS ternary core-shell QDs were synthesized respectively. The results indicate that proteins have no influence on the morphology, composition, and lattice of quantum dots. However, they can significantly increase the fluorescence intensity of quantum dots (by 1.5 times) and the fluorescence lifetime (by 3.5 times). In addition, protein modification sharply enhanced the stability of quantum dots in various media. Moreover, for the first time, the binding interaction between proteins and quantum dots was directly verified using the fluorescence quenching technique. Thereafter, the bacterial target and antibacterial function imparted to QDs by lysozyme were demonstrated. Finally, we verified the application potential of CIS/ZnS@Lys in different medical scenarios, which performed well in wound disinfection, imaging bacterial adhesion in medical catheters, and killing the adhered bacteria.

Indexed as

Anti-Bacterial AgentsMuramidaseQuantum DotsSerum Albumin, BovineAnimalsCattleCopperGreen Chemistry TechnologyIndiumStaphylococcus aureusSulfidesZinc CompoundsAnti-Bacterial AgentsCopperIndiumMuramidaseSerum Albumin, BovineSulfidesZinc Compoundszinc sulfideAntibacterialCuInS@ZnSI–III–VI ternary QDsODs bioapplicationProtein modification

Identifiers

PMID40522544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.