Evidence map›Paper›PMID 40522478›Full record

ArticleAmerican journal of epidemiology2025

The impact of census-tract level mortgage discrimination on cognitive function: accounting for measurement instability in small-area data via joint modeling.

Yueying Hu, Michael R Elliott, Helen C S Meier, Liang Chen, Monica E Walters, Ketlyne Sol, Laura B Zahodne

Abstract read
In one paragraph

Article in American journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yueying HuDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, United States.ORCID 0009-0008-9619-7667
Michael R ElliottDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0003-4128-5527
Helen C S MeierSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0003-4400-0216
Liang ChenSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0002-3690-9887
Monica E WaltersDepartment of Psychology, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0003-0395-5868
Ketlyne SolSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0001-6716-6927
Laura B ZahodneDepartment of Psychology, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0002-5763-4501

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody, RAYMOND L YUNG · 2004 to 2026
$29.2M
Statistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI A. FREEDMAN · 1999 to 2026
$23.2M
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2016 to 2020
$10.1M
Mechanisms of inequalities in ADRD risk across race and place in the Michigan Cognitive Aging ProjectR01AG082307 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Laura B Zahodne · 2023 to 2026
$3.8M
The impact of redlining and place-based systemic racism on health inequalities at mid-lifeR01AG080401 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Helen Carmon Spink Meier · 2023 to 2026
$2.4M
Risk and resilience mechanisms underlying race disparities in ADRD: An examination of neighborhood resources, social networks, brain integrity, and cognitionK01AG073588 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SOL, KETLYNE · 2021 to 2025
$637k
Claude D. Pepper Older Americans Independence Center P30AG024824Michigan Alzheimer's Disease Core Center P30AG053760Michigan Center on the Demography of Aging P30AG012846NIA NIH HHS K01 AG073588NIA NIH HHS P30 AG012846NIA NIH HHS P30 AG024824NIA NIH HHS P30 AG053760NIA NIH HHS R01 AG080401NIA NIH HHS R01AG080401, R01AG082307, and K01AG073588NIA NIH HHS R01 AG082307
6 · The paper itself

Abstract

Racial disparities in cognitive health reflect entrenched structural inequalities. This study investigates the association between census-tract level mortgage discrimination, operationalized as the mortgage density index ratio (MDIR), and cognitive outcomes among racially diverse older adults. Using data from the Michigan Cognitive Aging Project, a cohort of 644 participants was analyzed across 6 cognitive measures. Hypersegregation, driven in part by historical redlining and contemporary racial discrimination in housing and lending, introduces instability in ratio indices like MDIR. To address this, we employed a joint modeling approach that simultaneously estimates cognitive outcomes and latent mortgage rates for Black and White households. This method identified a significant association between MDIR and processing speed only among non-Hispanic Black participants, with a 1-unit MDIR increase corresponding to a 0.48 standard deviation improvement in processing speed (95% confidence interval, 0.05-0.93) while controlling for individual demographics. Contrarily, traditional regression methods failed to detect such effects. Simulations further demonstrated the superiority of joint modeling in managing measurement instability, showing notably lower bias and greater robustness in small- to moderate-sized census tracts. These findings underscore the importance of advanced statistical methods in quantifying structural racism and highlight the disproportionate effects of mortgage discrimination on cognitive outcomes among Black adults.

Indexed as

CognitionHealth Status DisparitiesHousingRacismAgedAged, 80 and overBlack or African AmericanCensusesFemaleHumansMaleMichiganMiddle AgedSmall-Area AnalysisWhitehealth disparitieshypersegregationjoint modelingmeasurement instability

Identifiers

PMID40522478
PMCPMC12634109

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.