Evidence map›Paper›PMID 40522393›Full record

ReviewSchmerz (Berlin, Germany)2025

[Pain reprocessing therapy - rethinking pain : A new psychotherapeutic approach for the treatment of chronic pain].

Antje Kallweit, Howard Schubiner

Abstract readEnglish AbstractReview
In one paragraph

Review in Schmerz (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Antje KallweitSchmerztherapie an der Hohenluft Hamburg, Hoheluftchaussee 52, 20253, Hamburg, Deutschland. dr.antjekallweit@schmerztherapie-hoheluft.de.
Howard SchubinerDepartment of Internal Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic pain affects millions of people worldwide. Nociplastic pain in particular, characterized by central sensitization and a dysfunctional alarm system, requires innovative therapeutic approaches.

objectiveThis review introduces pain reprocessing therapy (PRT) as a promising psychotherapeutic approach to specifically disrupt the pain-fear-pain cycle. The theoretical background, practical implementation, and effectiveness, evidence, and feasibility of this new therapeutic method for treating nociplastic conditions are described and discussed.

resultsPRT enables patients to develop a new understanding of pain and break the pain-fear-pain cycle. Studies and clinical experience demonstrate that this method can achieve a significant reduction in pain intensity. DISCUSSION: PRT provides an innovative framework for treating chronic pain by combining evidence-based methods and enhancing patient self-efficacy. It has the potential to integrate the biopsychosocial model more effectively into practice and transform the paradigm of pain therapy. Challenges include the diagnostic differentiation of nociplastic pain, the required paradigm shift, and the need for training and time resources. However, studies show promising results for sustainable, patient-centered pain therapy.

Indexed as

Chronic PainPain ManagementPsychotherapyCatastrophizationCombined Modality TherapyEvidence-Based MedicineFearHumansModels, BiopsychosocialPain MeasurementCentral sensitizationChronic painNeuroplasticityNociplastic painSelf-efficacy

Identifiers

PMID40522393
PMCPMC12279561

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.