Evidence map›Paper›PMID 40521980›Full record

ArticleInvestigative ophthalmology & visual science2025

Myopia Development During Transition From Kindergarten to Early Grades in Elementary School: Population-Based Evidence From an Epidemic Area in Taiwan.

Yu-Chieh Yang, Der-Chong Tsai, Shao-You Fang, Hsin-Yu Yang, Chiao-Yu Wang, Chia-Wei Lee, Pei-Wei Huang, Mong-Ping Shyong, Yen-Lin Chen, Nai-Wei Hsu

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Identifying and Managing Pre-Myopia: A Narrative Review.Clinical ophthalmology (Auckland, N.Z.) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu-Chieh YangDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
Der-Chong TsaiDepartment of Ophthalmology, National Yang Ming Chiao Tung University Hospital, Yilan, Taiwan.
Shao-You FangUniversity of California Davis Center for Healthcare Policy and Research, University of California-Davis, Sacramento, CA, United States.
Hsin-Yu YangDepartment of Ophthalmology, National Yang Ming Chiao Tung University Hospital, Yilan, Taiwan.
Chiao-Yu WangDepartment of Ophthalmology, National Yang Ming Chiao Tung University Hospital, Yilan, Taiwan.
Chia-Wei LeeDepartment of Ophthalmology, Fu Jen Catholic University Hospital, Fu Jen Catholic University, New Taipei City, Taiwan.
Pei-Wei HuangDepartment of Ophthalmology, Lotung Poh-Ai Hospital, Lo-Hsu Medical Foundation, Incorporation, Yilan, Taiwan.
Mong-Ping ShyongDepartment of Ophthalmology, National Yang Ming Chiao Tung University Hospital, Yilan, Taiwan.
Yen-Lin ChenPublic Health Bureau, Yilan County, Taiwan.
Nai-Wei HsuFaculty of Medicine, National Yang Ming Chiao Tung University School of Medicine, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study was to investigate the incidence of myopia, its association, and refractive progression among kindergarten non-myopic children after entering elementary schools in Yilan, Taiwan. Methods: A cohort study was conducted on first- and second-grade elementary school students. Ocular examinations and caregiver-administered questionnaires were performed between December 2023 and March 2024, with data linked to kindergarten records from Yilan Myopia Vision Improvement Program (YMVIP). Myopia was defined as spherical equivalent (SE) ≤ -0.5 diopters (D), and premyopia as -0.5 D < SE ≤ 0.75 D. Results: Of 1754 enrolled students, 1680 (95.73%) underwent ocular examinations, and 1554 (88.55%) were linked to kindergarten data. Among 1428 non-myopic preschoolers, the incidence density of myopia was 8.70% per person-year (95% confidence interval [CI] = 7.60%-9.80%). Children with incident myopia had a more negative baseline SE (0.33 ± 0.50 D vs. 1.02 ± 0.80 D, P < 0.001) and greater annual myopic progression (-0.60 ± 0.42 D/year vs. -0.20 ± 0.34 D/year). A multiple logistic regression model identified risk factors for incident myopia as premyopia in preschool (odds ratio [OR] = 9.641, 95% CI = 5.936-15.660, P < 0.001), having two myopic parents (OR = 1.819, 95% CI = 1.003-3.297, P = 0.049), and older age at the time of the elementary school examination (OR = 1.635, 95% CI = 1.224-2.183, P = 0.001). Spending more than 30 minutes/day outdoors on weekdays in preschool was protective against myopia (OR = 0.528, 95% CI = 0.366-0.762, P = 0.001). Conclusions: The incidence density of myopia in Yilan County was 8.70% per person-year. Risk factors included premyopia, having myopic parents, and less outdoor time in kindergarten.

Indexed as

MyopiaRefraction, OcularSchoolsStudentsChildChild, PreschoolDisease ProgressionFemaleFollow-Up StudiesHumansIncidenceMaleRisk FactorsSurveys and QuestionnairesTaiwan

Identifiers

PMID40521980
PMCPMC12178439

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.