Evidence map›Paper›PMID 40521977›Full record

ArticleInvestigative ophthalmology & visual science2025

Hyperopic Eyes Are Structurally More Dynamic Than Myopic Eyes During Accommodation: An In Vivo Investigation.

Tuyishime Didier Fidele Uwacu, Saugat Bhattacharyya, Kathryn J Saunders, Julie-Anne Little

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Longitudinal Evaluation of Static and Dynamic Accommodation in Young Children.Investigative ophthalmology & visual science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tuyishime Didier Fidele UwacuCentre for Optometry and Vision Science, Biomedical Sciences Research Institute, Ulster University, Coleraine, United Kingdom.
Saugat BhattacharyyaSchool of Computing, Engineering and Intelligent Systems, Ulster University, Derry∼Londonderry, United Kingdom.
Kathryn J SaundersCentre for Optometry and Vision Science, Biomedical Sciences Research Institute, Ulster University, Coleraine, United Kingdom.
Julie-Anne LittleCentre for Optometry and Vision Science, Biomedical Sciences Research Institute, Ulster University, Coleraine, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The impact of different refractive errors on accommodative structural changes remains unclear. Novel swept-source imaging technology in anterior segment optical coherence tomography (AS-OCT) has enabled in vivo investigation of the accommodating eye. This study investigated ocular structural change and corresponding functional responses during accommodation in individuals with emmetropia, myopia, and hyperopia. Methods: Adults (n = 46; mean age, 22.15 ± 3.00 years) with normal accommodation and a wide range of refractive errors (spherical equivalent refraction [SER]: -7.50 D to +7.88 D) were recruited. CASIA2 AS-OCT measured anterior segment changes during accommodation stimulated by the use of inbuilt accommodative targets and bespoke external stimuli at five different accommodative demands (0 D, 2 D, 3 D, 4 D, and 6 D) and under cycloplegia. Simultaneously, changes in refractive state were measured using the PowerRefractor3 photorefraction system. Results: Lens thickness (LT), anterior chamber depth (ACD), lens diameter (LD), anterior segment length (ASL), anterior lens radius of curvature (ALRC), and posterior lens radius of curvature (PLRC) changed significantly during accommodation (all P < 0.001). Accommodative changes in LT, ACD, and ASL were significantly associated with the level of SER (all P < 0.05), as more hyperopic eyes showed significantly greater per-diopter change than myopic eyes in LT (P = 0.014) and ACD (P = 0.039) for comparatively similar accommodative response (P > 0.9). The analysis of lens position showed that cycloplegia induced posterior displacement of the lens. The CASIA2 internal accommodative target and the external proximal target induced similar structural and functional accommodative responses. Conclusions: There are significant differences between structural changes seen in accommodating eyes with different types and magnitudes of refractive error, with hyperopic eyes showing greater changes in LT and ACD than myopic eyes during accommodation.

Indexed as

Accommodation, OcularAnterior Eye SegmentHyperopiaMyopiaAdultAnterior ChamberEmmetropiaFemaleHumansLens, CrystallineMaleRefraction, OcularTomography, Optical CoherenceYoung Adult

Identifiers

PMID40521977
PMCPMC12178432

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.