Evidence map›Paper›PMID 40521634›Full record

ArticleFuture medicinal chemistry2025

New cannabidiol structure-related terpene

Graziella Dos Reis Rosa Franco, Isabela Marie Fernandes, Mikaela Lucinda de Souza, Vanessa Silva Gontijo, Marina Amaral Alves, Hygor Marcos Ribeiro de Souza, Carla Gabriely Gaião Do Invencio, Anna Carolina Pereira Lontra, João Pedro Barros de Paiva, Larissa Do Nascimento Dos Santos and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Graziella Dos Reis Rosa FrancoLaboratory of Research in Medicinal Chemistry - PeQuiM, Federal University of Alfenas, Institute of Chemistry, Alfenas, Brazil.
Isabela Marie FernandesLaboratory of Research in Medicinal Chemistry - PeQuiM, Federal University of Alfenas, Institute of Chemistry, Alfenas, Brazil.
Mikaela Lucinda de SouzaLaboratory of Research in Medicinal Chemistry - PeQuiM, Federal University of Alfenas, Institute of Chemistry, Alfenas, Brazil.
Vanessa Silva GontijoLaboratory of Research in Medicinal Chemistry - PeQuiM, Federal University of Alfenas, Institute of Chemistry, Alfenas, Brazil.
Marina Amaral AlvesLaboratory of Metabolomics - LabMeta/LADETEC, Federal University of Rio de Janeiro, Institute of Chemistry, Rio de Janeiro, Brazil.
Hygor Marcos Ribeiro de SouzaLaboratory of Metabolomics - LabMeta/LADETEC, Federal University of Rio de Janeiro, Institute of Chemistry, Rio de Janeiro, Brazil.
Carla Gabriely Gaião Do InvencioLaboratório de Farmacologia da dor e da inflamação, Federal University of Rio de Janeiro, Institute of Biomedical Sciences, Rio de Janeiro, Brazil.
Anna Carolina Pereira LontraLaboratório de Farmacologia da dor e da inflamação, Federal University of Rio de Janeiro, Institute of Biomedical Sciences, Rio de Janeiro, Brazil.
João Pedro Barros de PaivaLaboratório de Farmacologia da dor e da inflamação, Federal University of Rio de Janeiro, Institute of Biomedical Sciences, Rio de Janeiro, Brazil.
Larissa Do Nascimento Dos SantosLaboratório de Farmacologia da dor e da inflamação, Federal University of Rio de Janeiro, Institute of Biomedical Sciences, Rio de Janeiro, Brazil.
Ana Clara Machado da SilvaLaboratório de Farmacologia da dor e da inflamação, Federal University of Rio de Janeiro, Institute of Biomedical Sciences, Rio de Janeiro, Brazil.
Thaís Biondino Sardella GiornoLaboratório de Farmacologia da dor e da inflamação, Federal University of Rio de Janeiro, Institute of Biomedical Sciences, Rio de Janeiro, Brazil.
Isabella Alvim GuedesGrupo de Modelagem Molecular em Sistemas Biológicos - LNCC, National Laboratory for Scientific Computing, Petrópolis, Brazil.
Laurent Emmanuel DardenneGrupo de Modelagem Molecular em Sistemas Biológicos - LNCC, National Laboratory for Scientific Computing, Petrópolis, Brazil.
Patrícia Dias FernandesLaboratório de Farmacologia da dor e da inflamação, Federal University of Rio de Janeiro, Institute of Biomedical Sciences, Rio de Janeiro, Brazil.
Claudio ViegasLaboratory of Research in Medicinal Chemistry - PeQuiM, Federal University of Alfenas, Institute of Chemistry, Alfenas, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is the organism's protective mechanism to restore cellular and tissue homeostasis. Cannabidiol has been reported for its ability to bind to diverse receptors related to or not related to the endocannabinoid system, with good safety being one of the most promising phytocannabinoids for therapeutical purposes. CBD has shown

Indexed as

AnalgesicsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalCannabidiolHydrazonesTerpenesAnimalsAntioxidantsInflammationMaleMiceMolecular StructurePainStructure-Activity RelationshipTRPV Cation ChannelsAnalgesicsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsCannabidiolHydrazonesTerpenesTRPV Cation Channelsanti-inflammatory activityantinociceptive activityCannabidiolCBD analoguesCBD-based N-acylhydrazone analoguesN-acyl-hydrazones

Identifiers

PMID40521634
PMCPMC12279265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.