Evidence map›Paper›PMID 40521545›Full record

ArticleACS omega2025

Fabrication of Aligned Polyhydroxybutyrate Fibrous Scaffolds via a Touchspinning Apparatus.

Md Mazbah Uddin, Ummay Mowshome Jahan, Vijay Mohakar, Amit Talukder, Yahya Absalan, Brianna Blevins, Nataraja S Yadavalli, Vladimir Reukov, Sergiy Minko, Suraj Sharma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Md Mazbah UddinDepartment of Textiles, Merchandising, and Interiors, University of Georgia, 305 Sanford Dr., Athens, Georgia 30602, United States.ORCID https://orcid.org/0000-0002-5740-1046
Ummay Mowshome JahanDepartment of Textile Engineering, Chemistry, and Science, North Carolina State University, Raleigh, North Carolina 27606, United States.
Vijay MohakarDepartment of Textiles, Merchandising, and Interiors, University of Georgia, 305 Sanford Dr., Athens, Georgia 30602, United States.
Amit TalukderDepartment of Textiles, Merchandising, and Interiors, University of Georgia, 305 Sanford Dr., Athens, Georgia 30602, United States.ORCID https://orcid.org/0000-0001-8339-0419
Yahya AbsalanDepartment of Chemistry, University of Georgia, 302 E Campus Rd suite 1299B, Athens, Georgia 30602, United States.ORCID https://orcid.org/0000-0003-2738-9645
Brianna BlevinsDepartment of Chemistry, University of Georgia, 302 E Campus Rd suite 1299B, Athens, Georgia 30602, United States.
Nataraja S YadavalliCytoNest, Inc., 425 River Rd, Athens, Georgia 30602, United States.
Vladimir ReukovDepartment of Textiles, Merchandising, and Interiors, University of Georgia, 305 Sanford Dr., Athens, Georgia 30602, United States.ORCID https://orcid.org/0000-0003-1695-6712
Sergiy MinkoDepartment of Textiles, Merchandising, and Interiors, University of Georgia, 305 Sanford Dr., Athens, Georgia 30602, United States.ORCID https://orcid.org/0000-0002-7747-9668
Suraj SharmaDepartment of Textiles, Merchandising, and Interiors, University of Georgia, 305 Sanford Dr., Athens, Georgia 30602, United States.ORCID https://orcid.org/0000-0002-1480-1891

Funding

Graduate Training at the Interface of Neuroscience, Optical Engineering and Data ScienceT32NS136080 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI David A Boas, Jerry L Chen · 2024 to 2026
$661k
NINDS NIH HHS T32 NS136080
6 · The paper itself

Abstract

Poly-(3-hydroxybutyrate) (PHB) fibers ranging from nano- to microscale were successfully fabricated using a touchspinning apparatus. The optimization of key spinning parametersincluding solution concentration (5-11% w/v), rotational speed (1300-2100 rpm), and feed rate (5-20 μL/min)enabled the production of aligned fibrous scaffolds. Morphological analysis via field emission scanning electron microscopy (FE-SEM) revealed fiber diameters in the range of 0.831-1.273 μm, which were influenced by spinning conditions. Thermal stability was confirmed using thermogravimetric analysis (TGA), with an onset degradation temperature of ∼290 °C. Differential scanning calorimetry (DSC) showed a melting peak of ∼172 °C and a crystallinity increase from 37.9% in the pellet to 42.5% in fibers of PHB. The scaffolds were functionalized with collagen to enhance bioactivity, and fibroblast (NIH3T3) viability was assessed through alamarBlue and Live/Dead assays. Metabolic activity increased significantly over 5 days (

Identifiers

PMID40521545
PMCPMC12163700

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.