ArticleACS omega2025
Simultaneous Determination of Yeast Inhibitors 5‑HMF and Furfural in Hydrolyzed Lignocellulosic Biomass using HPLC-PDA.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Synthesis,ACS omega · 2026Article
- Alkaline, Neutral and Acidic Extracts from Rubber Tree (ACS omega · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lignocellulosic biomass acid hydrolysis process, for either pretreatment or saccharification purposes, involves temperature and acidity, which can lead to carbohydrate dehydration into furfuraldehydes, such as 5-hydroxymethylfurfural (5-HMF) and furfural. Unfortunately, these compounds can reduce the biomass quality for biofuel production, potentially inhibiting yeast fermentation, which converts sugars into ethanol, leading to low yields. Given the need to control these substances, a methodology for the simultaneous determination of 5-HMF and furfural via high-performance liquid chromatography (HPLC) was developed and validated to monitor the formation of these unwanted byproducts directly after the hydrolysis process of the Hevea brasiliensis lignocellulosic matrix. The method showed adequate selectivity for both analytes. Linearity was confirmed by analysis of variance (
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Registered trials
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