Evidence map›Paper›PMID 40521516›Full record

ArticleACS omega2025

Eco-Friendly Approaches in Oncology: Developing Holmium (

Sara Rhaissa Rezende Dos Reis, Natália Cristina Gomes-da-Silva, Luciana Magalhães Rebelo Alencar, Alan Silva de Menezes, Frederico Duarte de Menezes, Kirill S Golokhvast, Eduardo Ricci-Junior, Ralph Santos-Oliveira

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara Rhaissa Rezende Dos ReisNuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Brazilian Nuclear Energy Commission, Rio de Janeiro, Rio de Janeiro 21941906, Brazil.
Natália Cristina Gomes-da-SilvaNuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Brazilian Nuclear Energy Commission, Rio de Janeiro, Rio de Janeiro 21941906, Brazil.ORCID https://orcid.org/0000-0002-9088-6671
Luciana Magalhães Rebelo AlencarDepartment of Physics Biophysics and Nanosystems Laboratory, Federal University of Maranhão, São Luis, Maranhão, 65065690, Brazil.ORCID https://orcid.org/0000-0001-8210-2016
Alan Silva de MenezesDepartment of Physics Biophysics and Nanosystems Laboratory, Federal University of Maranhão, São Luis, Maranhão, 65065690, Brazil.
Frederico Duarte de MenezesFederal Institute of Technology of Pernambuco, DACI/IFPE, Recife, Pernambuco 50740545, Brazil.
Kirill S GolokhvastAdvanced Engineering School (Agrobiotek), Tomsk State University, Lenin Avenue, 36, Tomsk, 634050, Russia.
Eduardo Ricci-JuniorSchool of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro 21941900, Brazil.
Ralph Santos-OliveiraNuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Brazilian Nuclear Energy Commission, Rio de Janeiro, Rio de Janeiro 21941906, Brazil.ORCID https://orcid.org/0000-0002-0905-481X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using recycled materials is increasingly recognized as a crucial strategy in today's global context. The production of glass on a global scale, estimated at approximately 209 million tons annually, underscores the urgent necessity to identify alternative applications for this material. In this milieu, the adoption of recycled glass for applications conducive to health emerges as a significant opportunity, offering dual advantages: mitigating the global surplus of glass and enhancing public health outcomes. In the realm of diseases, oncology, and hepatocellular carcinoma stand out due to their extensive costs and detrimental impact on health. Consequently, this research has been directed toward developing, comprehensively characterization, and in vivo assessment of Ho (Ho-166) holmium-166 doped glass microspheres derived from recycled glass. The findings confirmed the successful formation of these microspheres, marked by a high degree of holmium doping. Moreover, the studies revealed a significant accumulation of the microspheres in the liver, alongside a lack of toxicological effects. Collectively, these results strongly support the potential of recycled glass as a valuable resource for fabricating holmium-doped glass microspheres, offering a promising avenue for liver cancer treatment.

Identifiers

PMID40521516
PMCPMC12163816

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.