Evidence map›Paper›PMID 40521441›Full record

ArticleACS omega2025

Immobilization of Porcine Trypsin in Superparamagnetic Nanoparticles: Enzyme Activity and Stability.

Isabella F S Aversa, Marcello H S Cavalcanti, Thalles M Pereira, Alexandre A de Castro, Olga L Tavano, Yara L Coelho, Luis H M da Silva, Luiz F Gorup, Teodorico C Ramalho, Luciano S Virtuoso

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isabella F S AversaColloid Chemistry Group, Chemistry Institute, Federal University of Alfenas (UNIFAL-MG), 700 Gabriel Monteiro da Silva street, Alfenas, MG 37130-000 , Brazil.
Marcello H S CavalcantiColloid Chemistry Group, Chemistry Institute, Federal University of Alfenas (UNIFAL-MG), 700 Gabriel Monteiro da Silva street, Alfenas, MG 37130-000 , Brazil.
Thalles M PereiraColloid Chemistry Group, Chemistry Institute, Federal University of Alfenas (UNIFAL-MG), 700 Gabriel Monteiro da Silva street, Alfenas, MG 37130-000 , Brazil.ORCID https://orcid.org/0009-0005-8816-1152
Alexandre A de CastroDepartment of Chemistry, Federal University of Lavras, Lavras, MG 37200-000, Brazil.
Olga L TavanoColloid Chemistry Group, Chemistry Institute, Federal University of Alfenas (UNIFAL-MG), 700 Gabriel Monteiro da Silva street, Alfenas, MG 37130-000 , Brazil.ORCID https://orcid.org/0000-0003-4319-4661
Yara L CoelhoColloid Chemistry Group, Chemistry Institute, Federal University of Alfenas (UNIFAL-MG), 700 Gabriel Monteiro da Silva street, Alfenas, MG 37130-000 , Brazil.
Luis H M da SilvaAdvanced Thermokinetics of Molecular Systems (ATOMS) Group, Department of Chemistry, Federal University of Viçosa, PH Rolfs, Viçosa, MG 36570900, Brazil.ORCID https://orcid.org/0000-0002-8262-1091
Luiz F GorupDepartment of Chemistry, Federal University of Juiz de Fora (UFJF), Juiz de Fora, MG 36036-900, Brazil.ORCID https://orcid.org/0000-0003-2646-8026
Teodorico C RamalhoDepartment of Chemistry, Federal University of Lavras, Lavras, MG 37200-000, Brazil.ORCID https://orcid.org/0000-0002-7324-1353
Luciano S VirtuosoColloid Chemistry Group, Chemistry Institute, Federal University of Alfenas (UNIFAL-MG), 700 Gabriel Monteiro da Silva street, Alfenas, MG 37130-000 , Brazil.ORCID https://orcid.org/0000-0001-9814-1394

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores the immobilization of porcine trypsin (PT) on superparamagnetic iron oxide nanoparticles (SPIONs) via adsorption, with a focus on both immobilization conditions and a comprehensive energetic evaluationan aspect often neglected in the literature. Isothermal titration calorimetry (ITC) revealed that interactions at pH 8.0 are energetically favorable, with a Δ

Identifiers

PMID40521441
PMCPMC12163697

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.