SynthesisFrontiers in nutrition2025
Prognostic significance of the pretreatment controlling nutritional status score in colorectal cancer patients: an updated meta-analysis with 24 cohort studies.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of the Controlling Nutritional Status (CONUT) score in cancer: an umbrella review of systematic reviews and meta-analyses.Frontiers in nutrition · 2026Pooled it
- Predictors of Metastatic Lymph Node Burden in Colorectal Cancer: A Negative Binomial Regression Analysis.Life (Basel, Switzerland) · 2026Article
- Preoperative Immunonutritional Indices in Colorectal Cancer: The Contribution of Albumin, Time-Dependence of Effect, and Threshold Transportability in a Saudi Cohort.Current oncology (Toronto, Ont.) · 2026Article
- Age-Dependent Prognostic Significance of Preoperative Transthyretin After Curative Resection for Stage I-III Colorectal Cancer.Annals of gastroenterological surgery · 2026Article
- The miR-181d-5p/SPP1 axis inhibits the migration and invasion of colorectal cancer via the RhoA patyway.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The prognostic significance of the Controlling Nutritional Status (CONUT) score in colorectal cancer has been extensively reported, yet it remains unclear. This study aims to conduct an updated meta-analysis to evaluate the association between pretreatment CONUT score and long-term oncological outcomes in patients diagnosed with colorectal cancer. Methods: A comprehensive literature search was conducted in PubMed, Embase, and Web of Science to identify eligible studies from inception to September 01, 2024, with an update on December 23, 2024. The primary endpoints evaluated were survival outcomes. Hazard ratios (HRs) with corresponding 95% confidence intervals (CIs) for survival outcomes were either extracted or calculated. A random-effects model was applied to pool all of the results. Statistical analyses were performed using R software, version 4.2.1. Results: A total of 24 retrospective cohort studies including 9,628 colorectal cancer patients were included. The pooled results demonstrated that patients with higher CONUT score exhibited significantly poorer outcomes across multiple survival metrics: overall survival (HR = 1.73; 95%CI: 1.50-2.01; Conclusion: Our study demonstrates that the pretreatment CONUT score can serve as a valuable biomarker for predicting long-term oncological outcomes in patients with colorectal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.