Evidence map›Paper›PMID 40521333›Full record

ArticleBMJ public health2025

'Antibiotics are like gold': a qualitative study of patient perspectives on the use of antibiotics without a prescription.

Lindsey A Laytner, Patricia Chen, Barbara Wells Trautner, Susan Nash, Ashley Collazo, Fabrizia Faustinella, Kiara Olmeda, Azalia Mancera, Roger Zoorob, Michael K Paasche-Orlow and 1 more

Abstract read
In one paragraph

Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lindsey A LaytnerDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-3790-7090
Patricia ChenVA Center for Innovations in Quality Effectiveness and Safety, Houston, Texas, USA.
Barbara Wells TrautnerVA Center for Innovations in Quality Effectiveness and Safety, Houston, Texas, USA.
Susan NashDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Ashley CollazoDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Fabrizia FaustinellaDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Kiara OlmedaDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Azalia ManceraDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Roger ZoorobDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Michael K Paasche-OrlowDepartment of Medicine, Tufts Medical Center, Boston, Massachusetts, USA.
Larissa GrigoryanDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Using antibiotics without a prescription (non-prescription use) is common in the USA and contributes to antibiotic misuse, potentially harming individuals and threatening public health. At the individual level, safety issues related to non-prescription use include adverse drug reactions and disruption of healthy microbiomes. At the public health level, non-prescription use increases the risk of antimicrobial resistance. Objectives: This qualitative study explored the reasons and motivations underlying non-prescription use among adult outpatients with varying healthcare coverage and education. Methods: We used purposive sampling to recruit participants who endorsed using non-prescription antibiotics in a larger quantitative survey. Participants were patients recruited from six public and two private clinics in Houston and Katy, Texas. All interviews were semistructured and conducted remotely by trained research coordinators in the participant's preferred language (English or Spanish). Interviews captured elements from two domains of the Kilbourne Theoretical Framework for Advancing Health Disparities Research, including patients' attitudes and beliefs, resources and various healthcare-system factors that could impact non-prescription use. Thematic analysis revealed the factors and situations that contribute to non-prescription use. Results: Of 86 participants surveyed, 72% were female and 24% had Medicare or private insurance. Our thematic analyses on why participants use non-prescription antibiotics are organised into two domains: (1) patient beliefs and experiences and (2) healthcare system barriers. Patient beliefs and experiences revealed four themes: (1) belief that antibiotics relieve many symptoms/illnesses (eg, pain, sore throat, if symptoms/illnesses are persistent, lingering or severe), (2) belief that patients know their own bodies (eg, participants' perceived self-efficacy in knowing and using medications for their illnesses/symptoms), (3) belief that over-the-counter medicines do not work and (4) belief that antibiotics are like gold (eg, antibiotics are difficult to obtain, valuable and highly effective). Healthcare system barriers revealed two themes: (1) patients encounter obstacles to healthcare (eg, transportation, long wait times, high healthcare costs and lack of reliable telemedicine options) and (2) patients express convenience in using non-prescription antibiotics from multiple sources (eg, leftover prescriptions, social networks or purchased without a prescription). Conclusions: Barriers to care, the convenience of obtaining non-prescription antibiotics, and patients' beliefs regarding the powerful value of antibiotics and their agency to direct this aspect of care present challenges that need to be explored to design effective outpatient antibiotic stewardship programmes.

Indexed as

Community HealthHealth Services AccessibilityPublic HealthQualitative ResearchSocial Medicine

Identifiers

PMID40521333
PMCPMC12164297

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.