Evidence map›Paper›PMID 40521261›Full record

ArticleWorld journal of gastroenterology2025

Effect of sex on the outcomes of peroral endoscopic myotomy for the treatment of achalasia.

Chen-Yi Zhao, Ning Xu, Hao Dong, Ning-Li Chai, En-Qiang Linghu

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chen-Yi ZhaoDepartment of Digestive Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Ning XuDepartment of Digestive Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Hao DongDepartment of Digestive Diseases, Chinese PLA General Hospital, Beijing 100853, China.
Ning-Li ChaiDepartment of Digestive Diseases, Chinese PLA General Hospital, Beijing 100853, China.
En-Qiang LinghuDepartment of Digestive Diseases, Chinese PLA General Hospital, Beijing 100853, China. linghuenqiang@vip.sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeroral endoscopic myotomy (POEM) has emerged as the first-line therapy for achalasia. However, large-scale studies which examine sex-related differences in symptoms and outcomes remain limited.

aimTo evaluate the impact of sex on achalasia symptoms, diagnostic findings, and postoperative improvement following POEM.

methodsWe conducted a retrospective review of achalasia patients who underwent POEM at a large center between 2010 and 2020, analyzing demographics and variables collected before, during, and after the procedure for both female and male cases.

resultsOur study included 526 cases in total, with the female group experiencing more severe chest pain (

conclusionSex may influence the severity and frequency of chest pain, with female cases exhibiting higher LESP and IRP compared to male cases. POEM is proven to be a safe and effective procedure for both sexes, with female cases potentially experiencing greater benefits.

Indexed as

Esophageal AchalasiaMyotomyNatural Orifice Endoscopic SurgeryAdultAgedAge FactorsChest PainDeglutition DisordersEsophageal Sphincter, LowerFemaleHumansMaleManometryMiddle AgedRetrospective StudiesSeverity of Illness IndexAchalasiaEckardt scoreHigh-resolution esophageal manometryPeroral endoscopic myotomySex difference

Identifiers

PMID40521261
PMCPMC12159981

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.