Evidence map›Paper›PMID 40521204›Full record

ArticleTheranostics2025

Toll-like receptor 2 deficiency exacerbates corneal angiogenesis in injury by impairing regulatory T cells.

Jung Hwa Ko, Hyun Ju Lee, Hyeon Ji Kim, Jin Suk Ryu, Yoo Rim Choi, Chang Ho Yoon, Hyun Beom Song, Donghyun Kim, Ryang Hwa Lee, Joo Youn Oh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jung Hwa KoLaboratory of Ocular Regenerative Medicine and Immunology, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Hyun Ju LeeLaboratory of Ocular Regenerative Medicine and Immunology, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Hyeon Ji KimLaboratory of Ocular Regenerative Medicine and Immunology, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Jin Suk RyuLaboratory of Ocular Regenerative Medicine and Immunology, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Yoo Rim ChoiLaboratory of Ocular Regenerative Medicine and Immunology, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Chang Ho YoonLaboratory of Ocular Regenerative Medicine and Immunology, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
Hyun Beom SongDepartment of Tropical Medicine and Parasitology and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Korea.
Donghyun KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Ryang Hwa LeeDepartment of Cell Biology and Genetics, Institute for Regenerative Medicine, Texas A&M University School of Medicine, College Station, TX, USA.
Joo Youn OhLaboratory of Ocular Regenerative Medicine and Immunology, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Corneal InjuriesCorneal NeovascularizationT-Lymphocytes, RegulatoryToll-Like Receptor 2Adoptive TransferAnimalsCorneaDisease Models, AnimalMaleMiceMice, Inbred C57BLMice, KnockoutMonocytesToll-Like Receptor 4Tlr2 protein, mouseToll-Like Receptor 2Toll-Like Receptor 4AngiogenesisCorneaHomeostasisMonocyteRegulatory T cellToll-like receptor 2Vascular endothelial cell.

Identifiers

PMID40521204
PMCPMC12159752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.