Evidence map›Paper›PMID 40521185›Full record

ArticleTheranostics2025

Mannosylated neutrophil vesicles targeting macrophages alleviate liver inflammation by delivering CRISPR/Cas9 RNPs.

Dongqing Wu, Hang Shu, Mengmeng Zhang, Xiaoli Wei, Jingjing Ji, Haiyuan Shen, Hejiao Zhang, Linxi Xie, Liangliang Zhou, Lei Yang and 7 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Dongqing WuDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.
Hang ShuDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.
Mengmeng ZhangDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.
Xiaoli WeiDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.
Jingjing JiSchool of Pharmaceutical Sciences, Anhui Medical University, Hefei 230032, China.
Haiyuan ShenDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.
Hejiao ZhangDepartment of Gastroenterology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.
Linxi XieSchool of Basic Medical Science, Anhui Medical University, Hefei 230000, Anhui, China.
Liangliang ZhouDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.
Lei YangSchool of Basic Medical Science, Anhui Medical University, Hefei 230000, Anhui, China.
Jiali JiangSchool of Basic Medical Science, Anhui Medical University, Hefei 230000, Anhui, China.
Chen ChenSchool of Basic Medical Science, Anhui Medical University, Hefei 230000, Anhui, China.
Shanfei TianSchool of Basic Medical Science, Anhui Medical University, Hefei 230000, Anhui, China.
Xinru ZhangSchool of Basic Medical Science, Anhui Medical University, Hefei 230000, Anhui, China.
Xu LongSchool of Basic Medical Science, Anhui Medical University, Hefei 230000, Anhui, China.
Xiaoyan HeSchool of Life Sciences, Anhui Medical University, Hefei 230000, Anhui, China.
Hua WangDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRISPR-Cas SystemsMacrophagesNeutrophilsRibonucleoproteinsAnimalsCRISPR-Associated Protein 9Disease Models, AnimalGene EditingHepatitisHumansInflammasomesInflammationLiverMaleMannoseMiceCRISPR-Associated Protein 9InflammasomesMannoseNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseRibonucleoproteinshepatic macrophagesinflammatory liver diseasesmannosylated neutrophilNLRP3 gene

Identifiers

PMID40521185
PMCPMC12159820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.