Evidence map›Paper›PMID 40521123›Full record

ArticleMethodsX2025

RT-QuIC optimization for prion detection in soils.

Madeline K Grunklee, Stuart S Lichtenberg, Gage Rowden, Diana L Karwan, E Anu Li, Marc D Schwabenlander, Tiffany M Wolf

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Madeline K GrunkleeDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 1365 Gortner Avenue, St. Paul, MN 55108, USA.
Stuart S LichtenbergMinnesota Center for Prion Research and Outreach (MNPRO), 205 Veterinary Science Building, 1971 Commonwealth Avenue, St. Paul, MN 55108, USA.
Gage RowdenMinnesota Center for Prion Research and Outreach (MNPRO), 205 Veterinary Science Building, 1971 Commonwealth Avenue, St. Paul, MN 55108, USA.
Diana L KarwanMinnesota Center for Prion Research and Outreach (MNPRO), 205 Veterinary Science Building, 1971 Commonwealth Avenue, St. Paul, MN 55108, USA.
E Anu LiMinnesota Center for Prion Research and Outreach (MNPRO), 205 Veterinary Science Building, 1971 Commonwealth Avenue, St. Paul, MN 55108, USA.
Marc D SchwabenlanderMinnesota Center for Prion Research and Outreach (MNPRO), 205 Veterinary Science Building, 1971 Commonwealth Avenue, St. Paul, MN 55108, USA.
Tiffany M WolfDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 1365 Gortner Avenue, St. Paul, MN 55108, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wasting disease (CWD) is a transmissible neurodegenerative prion disorder affecting cervid species, such as deer, characterized by neurological decline and death. CWD prions (PrP

Indexed as

CervidContaminationCWDEnvironmentReal-time quaking-induced conversion assaySoil extractionSoil processing for prion detection by RT-QuIC

Identifiers

PMID40521123
PMCPMC12167030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.