Evidence map›Paper›PMID 40521062›Full record

ArticlePostepy dermatologii i alergologii2025

Risk factors and incidence of hepatitis B, hepatitis C and HIV among syphilis patients in Shanghai, China.

Juan Wu, Yan Hu, Liyan Ni, Lin Zhu, Wei Zhao, Xin Gu, Rui-Rui Peng, Fu-Quan Long

Abstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juan WuDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Yan HuDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Liyan NiDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Lin ZhuDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Wei ZhaoDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Xin GuDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Rui-Rui PengDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Fu-Quan LongDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: There is great need to screen for HIV, HBV, HBC and syphilis co-infected cases in china because of high prevalance of this disease. Aim: To uncover the risk factors and incidence of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) among syphilis patients. Material and methods: A total of 5,206 patients with syphilis were enrolled in this retrospective cohort study. The data of clinical and laboratory characteristics of the participants were collected. The correlations between the clinical characteristics and HBV, HCV and HIV co-infection with syphilis were analysed. Results: The prevalence of HBV, HCV and HIV among syphilis patients in our study was 8.4%, 1.8%, and 10.1%, respectively. The median age was significantly lower in the HBV/syphilis co-infected group (47.5 with IQR 36-58 vs. 52 with IQR 36-61), the majority of co-infected individuals were male (251, 57.6% vs. 185, 42.4%). Multivariate logistic regression analysis showed that co-infected with patients co-infected with HCV and combined with gonococcal infection and herpes virus type II infection were independently associated with HBV co-infection in syphilis patients. Multivariate logistic regression analysis found that male gender, age below 30 years, age group of 31-44-years old, co-infection with HSV-2, never married and divorced, and having a RPR titre of ≥ 1 : 32 were independently associated with HIV co-infection. Conclusions: HIV co-infection or homosexuality among syphilis patients had no significant impact on the prevalence of HBV or HCV in the study.

Indexed as

co-infectionhepatitis B virushepatitis C virusHIVsyphilis

Identifiers

PMID40521062
PMCPMC12163968

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