ArticleJournal of surgical case reports2025
Exuberant delayed granulomatous reaction to hyaluronic acid filler material.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Dermal fillers are increasing in popularity, especially among young females. Hyaluronic acid is a commonly used injectable material with a relatively safe profile and rare adverse events. In this case, a 34-year-old female patient presented to the oral and maxillofacial clinic in Hafar Al-Batin, Saudi Arabia, with right-sided facial swelling for 1 year. Patient history revealed injection of dermal cosmetic material for 10 years. Magnetic resonance imaging revealed a subcutaneous collection with an irregular wall and adjacent fat stranding. The swelling was removed under general anesthesia, and the tissue was sent for histological diagnosis. The pathological findings included a collection of multinucleated giant cells surrounding cystic spaces filled with frothy, deep blue secretion consistent with foreign body granuloma to hyaluronic acid.
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