Evidence map›Paper›PMID 40521031›Full record

ArticleFrontiers in cellular and infection microbiology2025

Shreya Dinesh, Lalitha Prajna, Prajna Namperumalsamy Venkatesh, Kuppamuthu Dharmalingam, Bharanidharan Devarajan

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shreya DineshDepartment of Microbiology and Bioinformatics, Aravind Medical Research Foundation, Madurai, India.
Lalitha PrajnaDepartment of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.
Prajna Namperumalsamy VenkateshCornea and Refractive Surgery Services, Aravind Eye Hospital, Madurai, India.
Kuppamuthu DharmalingamDepartment of Proteomics, Aravind Medical Research Foundation, Madurai, India.
Bharanidharan DevarajanDepartment of Microbiology and Bioinformatics, Aravind Medical Research Foundation, Madurai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fungal keratitis, caused primarily by Methods: This study employed high-throughput RNA sequencing to investigate differential gene expression in human corneal tissues from patients with Results: Data analysis identified common and Discussion: RT-qPCR confirmed the key pathogen-specific DEGs, highlighting their potential as biomarkers for pathogen-specific immune responses. These findings provide insights into the distinct immune pathways triggered by

Indexed as

AspergillosisAspergillus flavusEye Infections, FungalFusariosisFusariumHost-Pathogen InteractionsKeratitisCorneaFemaleGene Expression ProfilingHumansMaleMiddle Ageddifferential gene expressionfungal keratitis (FK)IL-17 signalling pathwaypathogen specific host immune responseRT-qPCR analysis

Identifiers

PMID40521031
PMCPMC12162692

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.