ArticleJHLT open2025
Diaphragm dysfunction from phrenic nerve injuries during LVAD or heart transplant: Positive role of diaphragm pacing.
Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Evaluating diaphragm motor response variability in electric and magnetic phrenic nerve stimulations during passive expiration.Clinical neurophysiology practice · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Phrenic nerve dysfunction in left ventricular assist device (LVAD) implantation or heart transplant (HTx) leads to dependency on noninvasive ventilation and difficulty weaning off mechanical ventilation (MV). This study reports on diaphragm pacing (DP) to improve diaphragm function postphrenic nerve injury. Methods: In a single-center cohort study, 2 DP systems were used in HTx or LVAD recipients. Chronic DP was laparoscopically implanted for remote phrenic dysfunction, while temporary DP was implanted percutaneously during HTx. Diaphragm function was evaluated radiographically and via electromyography. Results: Out of 900 patients, 10 met criteria and used DP without adverse events. Eight had chronic DP for phrenic injuries (5 HTx, 3 LVAD), with 87% recovery. Two had temporary DP at HTx; one utilized DP for weaning from MV. Early DP use facilitated rapid MV weaning. Conclusions: This exploratory case series suggests a potential role for DP in patients with phrenic nerve injury following heart transplant or LVAD.
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