Evidence map›Paper›PMID 40520773›Full record

ArticleDialogues in health2025

Addressing the challenge of rheumatic heart disease in Pakistan: A call to action.

Abdul Hakeem, Masood Sadiq, Javerya Hassan, Isbaah Tejani, Ijaz Hussain, Jalil Khan, Mohammad Waleed, Sabha Bhatti, Sana Sheikh, Sobia Masood and 4 more

Abstract read
In one paragraph

Article in Dialogues in health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abdul HakeemNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Masood SadiqUniversity of Child Health Sciences, The Children's Hospital, Lahore, Pakistan.
Javerya HassanCITRIC Health Data Science Centre, The Aga Khan University, Karachi, Pakistan.
Isbaah TejaniCITRIC Health Data Science Centre, The Aga Khan University, Karachi, Pakistan.
Ijaz HussainPeshawar Institute of Cardiology, Peshawar, Pakistan.
Jalil KhanInsitute of Family Medicine, Khyber Medical University, Peshawar, Pakistan.
Mohammad WaleedPeshawar Institute of Cardiology, Peshawar, Pakistan.
Sabha BhattiNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Sana SheikhCITRIC Health Data Science Centre, The Aga Khan University, Karachi, Pakistan.
Sobia MasoodNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Ali H MokdadInstitute for Health Metrics and Evaluation, Seattle, WA, USA.
Aziz SheikhUniversity of Oxford, Oxford, UK.
Zafar MirzaShifa Tameer-e-Millat University (STMU), Islamabad, Pakistan.
Zainab SamadCITRIC Health Data Science Centre, The Aga Khan University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite its high prevalence, Acute rheumatic fever (ARF) and Rheumatic heart disease (RHD) is underrepresented in Pakistan's national and federal health plans. To address this gap, we gathered multi-geographic and specialty perspectives from frontline clinicians in Pakistan'. Major challenges in RHD diagnosis and care include regional healthcare disparities, diagnostic limitations, scarcity of Benzathine Penicillin G (BPG) for prophylaxis, and lack of multidisciplinary RHD teams. Our practitioner-informed recommendations emphasize community outreach, targeted screening, and surveillance, and comprehensive training for healthcare providers in the diagnosis and management of GAS infections and ARF. Strengthening multidisciplinary care and ensuring stable BPG supplies are essential, as is integrating RHD care into Universal Health Coverage (UHC) models currently being implemented to reduce patient financial burdens. Improving RHD management requires systemic changes to healthcare infrastructure, practitioner training, and coordinated policy efforts. Crucially, these proposals align with WHO's latest RHD guidelines on primary (treating GAS infections) and secondary prevention (antibiotic prophylaxis and screening). By translating local clinical wisdom into actionable policies, this viewpoint yields practical interventions tailored to Pakistan that are also adaptable to similar LMIC settings.

Indexed as

Benzathine penicillin G secondary prophylaxisLow-middle income countriesPakistanRheumatic feverRheumatic heart disease

Identifiers

PMID40520773
PMCPMC12164228

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.