ArticleJournal of orthopaedic case reports2025
Comparative Study of Functional Outcome and Pain Control with Non-steroidal Anti-inflammatory Drugs (NSAIDs) and Non-NSAIDs in Early Post-operative Period in Total Knee Arthroplasty.
Article in Journal of orthopaedic case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Primary aim - To evaluate the pain control with non-steroidal anti-inflammatory drugs (NSAIDs) and non-NSAIDs in early post-operative period during hospital stays in total knee arthroplasty (TKA) and compare them. Secondary aim - To evaluate the functional outcome with NSAIDs and non-NSAIDs in early post-operative period after 28 days, 3 months, and 6 months in TKA and compare them. Objectives: The objectives are as follows: (1) To assess the effectiveness of NSAIDs and non-NSAIDs in pain control during early post-operative period after TKA, using Visual Analog Scale (VAS) during hospital stay-every 4 hourly. (2) To compare the VAS pain scores in NSAIDs and non-NSAID patients during hospital stays. (3) To assess the functional outcome in NSAIDs and non-NSAIDs patients using Oxford Knee Score (OKS) and knee society score (KSS) after 28 days, 3 months, and 6 months. (4) To compare the functional outcome obtained by OKS and KSS in NSAIDs and non-NSAIDs patients after 28 days, 3 months, and 6 months. Materials and Methods: Study duration: This study was 12 months (April 1st, 2023-March 31st, 2024). Study design: This was a comparative prospective study. Conclusion: Evaluation of Oxford KSSs for pain management post-surgery for long duration showed statistically significant 44 difference in the OKS score at 1 month and 3-months (p = 0.05) between the two groups. Thus, at 6 months, the NSAID and non-NSAID group patients report similar pain scores with minimal or no pain.
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