ArticleJournal of orthopaedic case reports2025
Evaluation of Efficacy of Tranexamic Acid on Blood Loss in Surgically Managed Intertrochanteric Fractures.
Article in Journal of orthopaedic case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Tranexamic Acid for Reduction of Blood Loss in Patients with Extracapsular Proximal Femur Fractures: Systematic Review and Meta-Analysis of Randomized Clinical Trials.Pharmaceutics · 2026Article
- Effect of Routes of Administration of Tranexamic Acid in Peri-Operative Blood Loss in Total Hip Arthroplasty: A Prospective Comparative Study.Journal of orthopaedic case reports · 2026Article
- Intraoperative tranexamic acid use in elderly patients with intertrochanteric fractures: impact on early postoperative inflammation and clinical outcomes.Frontiers in physiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Intertrochanteric (IT) fracture surgeries make up a significant portion of trauma operations worldwide. The routine use of tranexamic acid (TXA) for these surgeries is not common in current practice at most places. This prospective study evaluated its efficacy in reducing perioperative blood loss and accentuating its potential for a better outcome. Materials and Methods: A total of 100 patients were divided equally into two groups, A and B. Group A was given preoperative intravenous (IV) TXA and intraoperative topical TXA through the drain, while Group B was given preoperative and intraoperative normal saline. Both groups were comparable in age, body mass index, preoperative hemoglobin (Hb), surgery performed, and duration of surgery. Results: The mean drain volume, postoperative Hb, fall of Hb, and total blood loss were all significantly less in Group A as compared to Group B (P < 0.01). None of the patients in either group received more than one unit of blood transfusion. No complications were seen in any of the patients till the final follow-up. Conclusion: In comparison to other studies, our study is in agreement that TXA overall helps in blood conservation; however, our study is unique in the way that the combination of preoperative IV and intraoperative topical TXA has resulted in the best possible results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.