Evidence map›Paper›PMID 40520566›Full record

ArticleMaterials today. Bio2025

Cu-Fe bimetallic peroxide-based nanozyme with microenvironment-triggered cascade catalysis for synergistic hydroxyl radical, nitric oxide, and oxygen generation in trimodal wound infection therapy.

Wei Liu, Yuan Fang, Ping Xu, Wanqin Cai, Yunping Peng, Wei Xue, Siming Yu

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Materials today. Bio · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei LiuDepartment of Orthopedics, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, China.
Yuan FangKey Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Ping XuDepartment of Orthopedics, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, China.
Wanqin CaiKey Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Yunping PengKey Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Wei XueKey Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Siming YuDepartment of Orthopedics, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, chemodynamic therapy (CDT) and gas therapy (GT) have garnered significant attention for antibacterial applications. However, effectively integrating CDT and GT into a single nanocomposite for synergistic therapy remains challenging. Herein, Cu-Fe bimetallic peroxide nanoparticles (CFp)-decorated hollow polydopamine (HPDA) nanozyme (CFp/HPDA) was fabricated and used as the carrier for nitric oxide (NO) donor BNN6 loading, resulting in the NO-releasing nanozyme of CFp/HPDA@BNN6. In the acidic bacterial infection microenvironment (BIME), CFp could rapidly dissociate by releasing Cu

Indexed as

Antibacterial and wound healingChemodynamic therapyDrug delivery and control releaseGas therapyNanozyme

Identifiers

PMID40520566
PMCPMC12166455

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.