Evidence map›Paper›PMID 40520553›Full record

ArticleMaterials today. Bio2025

Injectable functionalised Lycium barbarum polysaccharide/alginate hydrogel particles for the treatment of bone defects.

Kai Xie, Zhengwei Liu, Yansong Wang, Lei Zhu, Jiazhao Yang, Yongxiang Wang, Mingming Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Bioactive spectrum of goji berries (Food chemistry: X · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai XieDepartment of Orthopedics, Northern Jiangsu People's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University, Yangzhou, 225009, China.
Zhengwei LiuDepartment of Orthopedics, Northern Jiangsu People's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University, Yangzhou, 225009, China.
Yansong WangShenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, China.
Lei ZhuDepartment of Orthopedics, Northern Jiangsu People's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University, Yangzhou, 225009, China.
Jiazhao YangDepartment of Orthopaedics, The First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, Anhui, China.
Yongxiang WangDepartment of Orthopedics, Northern Jiangsu People's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University, Yangzhou, 225009, China.
Mingming ZhangDepartment of Rheumatology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of bone defects presents a number of significant clinical challenges. In recent years, plant-derived hydrogels have demonstrated considerable potential as a means of intervening in bone defects. In this study, a alginate hydrogel (Alg) system containing the Chinese medicinal plant Lycium barbarum was prepared with the objective of promoting the repair of bone defects. The hydrogel system was composed of Lycium barbarum polysaccharide (LBP), sodium alginate, and Srcl

Indexed as

Barbarum polysaccharidesBone defectsHydrogelSodium alginateTissue engineering

Identifiers

PMID40520553
PMCPMC12163170

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.