Evidence map›Paper›PMID 40520511›Full record

ArticleFrontiers in bioinformatics2025

Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise.

David Kirchenbuechler, Mariana De Niz, Constadina Arvanitis

Abstract read
In one paragraph

Article in Frontiers in bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David Kirchenbuechler *Center for Advanced Microscopy and Nikon Imaging Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Mariana De Niz *Center for Advanced Microscopy and Nikon Imaging Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Constadina Arvanitis *Center for Advanced Microscopy and Nikon Imaging Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
NCI NIH HHS P30 CA060553
6 · The paper itself

Abstract

Scientific studies are increasingly complex, involving quantification of many different experimental approaches and technologies. However, it is challenging for any individual scientist to build and retain sufficient expertise and competency in a large range of scientific tools. A deep expertise is critical for rigor and reproducibility; however, focused expertise can easily become a hindrance to inter-disciplinary science. This is particularly true with respect to microscopy and image analysis. Core facilities often bridge this gap, serving as an access point to expertise in cutting-edge technologies while facilitating collaboration. Our purpose with this perspective piece is to share our experience with other Microscopy Core Facility Directors and Image analysts who are aiming to establish image analysis training as a service. We hope that this shared experience can help others optimize their service though our lessons learned, and avoid pitfalls we faced during our Core's timeline. In this paper we explore three elements that have been vital for the establishment and expansion of image analysis at the Center for Advanced Microscopy at Northwestern University. The first is a commitment to dedicated image analysis service. The second is establishing image analysis training programs for the local scientific community, which facilitates integration of analysis into microscopy workflows. The third is engagement with international organizations such as BINA. These organization foster collaborations which ultimately result in the fruitful dissemination of novel tools across the community. These three elements are essential to maximize the potential of imaging-based scientific research and ultimately ensuring equal access to image informatics.

Indexed as

analysisbioinformaticsfacilitiesmicroscopyresearch

Identifiers

PMID40520511
PMCPMC12162573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.