ArticleEnvironmental epidemiology (Philadelphia, Pa.)2025
Disparities in the association of ambient air pollution with childhood asthma incidence in the ECHO consortium: A US-wide multi-cohort study.
Article in Environmental epidemiology (Philadelphia, Pa.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Outdoor air pollutants and asthma risk in adolescents: evidence from a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Effects of short-term exposure to air pollution on respiratory symptoms and lung function among patients with asthma.Medical gas research · 2026Article
- Advancing child health: forecasting the next great research achievements.Pediatric research · 2026Article
- Environmental and socioeconomic influences on childhood asthma and pneumonia: burden and healthcare utilization in a population-based cohort study.Frontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
35 authors.
Funding
Abstract
Background: Characterization of US sociodemographic disparities in air pollution respiratory effects has often been limited by lack of participant diversity, geography, exposure characterization, and small sample size. Methods: We included 34 sites comprising 23,234 children (born 1981-2021) from the Environmental influences on Child Health Outcomes (ECHO) Program with data on asthma diagnosis until age 10 (182,008 person-years). Predicted annual exposure to fine particulate matter (1988-2021), nitrogen dioxide (2000-2016), and ground ozone (2000-2016) were assigned based on residential histories. For each pollutant, we fitted time-varying Cox models adjusted for time trend, site, and several area- and individual-level sociodemographic features that were separately considered as modifiers via an interaction with exposure. Results: The hazard ratio of incident asthma by age 10 years was 1.19 (95% CI = 1.10, 1.28), 1.19 (95% CI = 1.05, 1.34), and 1.11 (95% CI = 1.01, 1.22) of an interquartile range increase in prior-year exposure to fine particulate matter (6.17 µg/m Conclusions: US efforts to mitigate childhood asthma risk by reducing air pollution would benefit from addressing root structural causes of vulnerability and susceptibility, including spatial patterning in air pollution sources and exposures as well as social and economic disadvantage.
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Registered trials
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