Evidence map›Paper›PMID 40520465›Full record

ReviewTherapeutic advances in gastrointestinal endoscopy

Navigating celiac disease with small bowel capsule endoscopy: current state and future horizons.

Matilde Topa, Mattia Corradi, Luca Elli, Yasmine Raji, Emanuele Lettieri, Nicoletta Nandi, Lucia Scaramella

Abstract readReview
In one paragraph

Review in Therapeutic advances in gastrointestinal endoscopy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matilde TopaDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0001-8761-1872
Mattia CorradiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-2261-0761
Luca ElliDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-0873-0759
Yasmine RajiDepartment of Management, Economics, and Industrial Engineering, Politecnico di Milano, Milan, Italy.
Emanuele LettieriDepartment of Management, Economics, and Industrial Engineering, Politecnico di Milano, Milan, Italy.
Nicoletta NandiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-4450-2593
Lucia ScaramellaGastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, via Francesco Sforza, 28, Milan 20122, Italy.ORCID https://orcid.org/0000-0002-9460-3296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CeD) is a widely diffused chronic autoimmune disorder triggered by the ingestion of gluten, in genetically predisposed individuals. Small bowel capsule endoscopy (SBCE) plays a pivotal role as a noninvasive tool for diagnosing and monitoring CeD. This review aims to summarize the current and potential future role of SBCE in the field of CeD. SBCE offers the advantage of visualizing the entire small bowel, allowing the extent of disease involvement to be described. According to international guidelines, SBCE has a defined role in cases of inconclusive histopathology or when clinical suspicion persists despite negative duodenal biopsies. To date, more and more interest is shown toward its role in monitoring CeD, specifically in terms of mucosal healing, early detection of complications such as ulcerative jejunitis, or performing differential diagnosis among other small bowel diseases that mimic CeD. With the rise of artificial intelligence systems being applied in this field, the future role of SBCE in CeD is expected to improve diagnostic accuracy and streamline the evaluation process, allowing its use as a routine tool for monitoring and early diagnosis of CeD-related complications. The environmental impact of SBCE is still under debate, but increasing evidence is suggesting ways to apply circular economy to the capsule lifecycle, turning it into a more sustainable device. In conclusion, SBCE is increasingly recognized as a critical tool in the diagnosis and monitoring of CeD.

Indexed as

celiac diseaseceliac disease diagnosisceliac disease monitoringnovel technologiesSBCE sustainabilitysmall bowel capsule endoscopy

Identifiers

PMID40520465
PMCPMC12163262

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.