Evidence map›Paper›PMID 40520450›Full record

ArticleJournal of the Endocrine Society2025

Global Rise of Compounded Weight-Loss Medicines: A Worrisome Trend.

Nikhil Sood, Rohini Garg

Abstract read
In one paragraph

Article in Journal of the Endocrine Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nikhil SoodDepartment of Hospital Medicine, Banner Gateway Medical Center, Banner Health, Gilbert, AZ 85034, USA.ORCID https://orcid.org/0009-0007-9456-5828
Rohini GargDepartment of Internal Medicine, CHI Health Mercy Hospital, Council Bluffs, IA 51503, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rise of compounded weight-loss drugs has emerged as a pressing global health issue, threatening consumers and health-care systems. Factors fueling this crisis include the desire for rapid weight-loss options, inadequate regulatory frameworks, and the easy availability of compounded products through online platforms and social media. Vulnerable populations, particularly those searching for low-cost treatments, are hit hardest. Tackling this escalating problem calls for a comprehensive strategy: enhancing regulatory oversight, raising public awareness, and fostering stakeholder collaboration. We can reduce the health dangers of compounded weight-loss medications by addressing the underlying causes and improving consumer safety. This article examines the risks associated with compounded weight-loss drugs and suggests practical measures to protect public health.

Indexed as

compounded drugssemaglutidetirzepatideweight loss drugs

Identifiers

PMID40520450
PMCPMC12164287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.