ArticleProceedings. IEEE International Symposium on Biomedical Imaging2025
LEVERAGING CONTRAST AGENT KINETICS FOR ROBUST REFLECTANCE MODE FLUORESCENCE TOMOGRAPHY.
Article in Proceedings. IEEE International Symposium on Biomedical Imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Fluorescence Image Guided Surgery utilizes continuous wave epi-fluorescence measurements on the tissue surface to locate targets such as tumors or lymph nodes, but precise 3D localization of deep targets remains intractable due to the illposedness of the associated inverse problem. We propose a Fluorescence Diffuse Optical Tomography scheme which leverages the different contrast agent kinetics in malignant vs normal tissue and reconstructs the 3D tumor location from a time series of epi-fluorescence measurements. We conduct sequential synthetic experiments, which mimic the differential uptake and release profile of fluorescent dye ICG in tumors vs normal tissue and demonstrate for the first time that the proposed method can robustly recover targets up to 1cm deep and in the presence of realistic tumor-to-background ratios.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.