Evidence map›Paper›PMID 40520341›Full record

ArticleOpen medicine (Warsaw, Poland)2025

The prognostic value of the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and prognostic nutritional index for survival in patients with colorectal cancer.

Xianya Zhu, Qiuping Xu, Yi Zhou, Chunrong Zhu, Lili Zeng

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xianya ZhuDepartment of Hematology and Oncology, Suzhou Wuzhong People's Hospital, Suzhou, 215000, China.
Qiuping XuDepartment of Hematology and Oncology, Suzhou Wuzhong People's Hospital, Suzhou, 215000, China.
Yi ZhouDepartment of Hematology and Oncology, Suzhou Wuzhong People's Hospital, Suzhou, 215000, China.
Chunrong ZhuDepartment of Oncology, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Canglang District, Suzhou, Jiangsu, 215000, China.
Lili ZengDepartment of Hematology and Oncology, Suzhou Wuzhong People's Hospital, Suzhou, 215000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To analyze the impact of the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and body mass index on the prognosis of colorectal cancer patients and to assess their clinical value. This cohort study included patients who underwent radical resection (R0 resection) for colorectal cancer. Peripheral blood laboratory test results for all patients were obtained within 1 week prior to surgery for the calculation of the NLR, PLR, and PNI. A total of 201 patients were included in the analysis. A total of 19 patients experienced relapse, and 30 patients died. The median follow-up duration was 39.2 months. Receiver operating characteristic curve analysis indicated that the PNI demonstrated moderately high predictive accuracy for overall survival (OS), with an area under the curve of 67.31%. After stratification based on the cutoff value, patients with a PNI of ≥44.48 exhibited a better survival prognosis than those with a PNI of <44.48 (

Indexed as

biomarkercolorectal cancerinflammatorynutritionprognosis

Identifiers

PMID40520341
PMCPMC12163575

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.