ArticleFrontiers in public health2025
Global burden of disease study on COPD in the older adult: comprehensive analysis of environmental factors and interaction effects.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy of single exercise interventions on pulmonary function and quality of life in patients with chronic obstructive pulmonary disease: a systematic review and network meta-analysis.Frontiers in medicine · 2026Pooled it
- Emergency Preparedness in Older Adults With and Without COPD During Power Outages and Natural Disasters.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Global, regional and national burden of chronic obstructive pulmonary disease and lower respiratory infection attributable to household air pollution and secondhand smoke from 1990 to 2021: an analysis of the Global Burden of Disease Study (GBD 2021).Journal of thoracic disease · 2026Article
- Global trends and inequalities in environmental risk-attributable chronic obstructive pulmonary disease mortality among adults aged 80+ years, 1990-2021: an analysis of the Global Burden of Disease Study 2021.Journal of thoracic disease · 2026Article
- Associations between physical activity and mortality in chronic obstructive pulmonary disease population with comorbidities: a prospective cohort.Journal of thoracic disease · 2026Article
- Chronic Obstructive Pulmonary Disease and Asthma Among Workers and Residents of Navanakorn Industrial Zone, Thailand.Medical sciences (Basel, Switzerland) · 2026Article
- COPD in China: the analysis of mortality and burden of disease trends from 2008 to 2021.Respiratory research · 2026Article
- Integrated Care for COPD in the Elderly: Impact on Healthcare Utilization Across Healthcare Settings.International journal of chronic obstructive pulmonary disease · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic obstructive pulmonary disease (COPD) is a leading global health issue, ranking fourth in mortality in 2021 per GBD 2021, with older adults most at risk due to aging-related vulnerabilities. Environmental factors like air pollution and temperature extremes are key contributors, with evidence suggesting their interaction worsens COPD. As the older adult population is projected to reach 2.1 billion by 2050, understanding these impacts is vital for public health. Method: Using GBD 2021 data, we analyzed COPD burden in older adults (1990-2021) due to air pollution and non-optimal temperature. Joinpoint regression and Bayesian models assessed trends in age-standardized mortality (ASMR) and disability-adjusted life year (ASDR) rates globally, regionally, and nationally. Spearman's correlation evaluated socio-demographic index (SDI) associations, and standardized exposure value (SEV) data examined air pollution-temperature interactions. Result: Globally, most environmental COPD burdens declined or stabilized, but high temperature burdens rose (AAPC > 0, Conclusion: This study reveals shifting COPD burdens, with ambient PM2.5 and high temperatures emerging as key challenges, particularly in lower-SDI areas. Synergistic air pollution-temperature effects highlight the need for integrated policies. These findings support targeted interventions to reduce COPD burden and enhance health equity in aging populations.
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