Evidence map›Paper›PMID 40520254›Full record

ArticleIJID regions2025

Temporal trends and public health implications of dengue in Guatemala: A decade of challenges and emerging threats (2013-2024).

Silvia Patricia Zuniga Veliz, Leticia Del Carmen Castillo Signor, Nancy Gonzalez, Joxua Araque, Francisco Hernández, Jorge Ramos, Nevis Nuñez, Francisca Vasquez, Alejandra Barrientos, Edson Jose Adrian Bolanos Lima and 4 more

Abstract read
In one paragraph

Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Silvia Patricia Zuniga VelizBioBox Guatemala, Guatemala City, Guatemala.
Leticia Del Carmen Castillo SignorMinistry of Public Health and Social Assistance of Guatemala (MSPAS), Guatemala City, Guatemala.
Nancy GonzalezBioBox Guatemala, Guatemala City, Guatemala.
Joxua AraqueBioBox Guatemala, Guatemala City, Guatemala.
Francisco HernándezBioBox Guatemala, Guatemala City, Guatemala.
Jorge RamosBioBox Guatemala, Guatemala City, Guatemala.
Nevis NuñezBioBox Guatemala, Guatemala City, Guatemala.
Francisca VasquezBioBox Guatemala, Guatemala City, Guatemala.
Alejandra BarrientosBioBox Guatemala, Guatemala City, Guatemala.
Edson Jose Adrian Bolanos LimaBioBox Guatemala, Guatemala City, Guatemala.
Edgar Santos TejedaDirectorate of Epidemiology and Risk Management of the Ministry of Public Health and Social Assistance, Guatemala City, Guatemala.
Mayra Lissette Motta PadillaFaculty of Veterinary Medicine and Zootechnics of Guatemala, Guatemala City, Guatemala.
Anoop AmbikanSystems Virology Lab, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.
Ujjwal NeogiSystems Virology Lab, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dengue, a rapidly spreading arboviral disease transmitted by Objectives: This study aimed to identify a temporal trend of the dengue epidemic in Guatemala over a decade (2013-2024). Methods: We collected month- and year-wise dengue case data from 29 provinces between 2013 and October 15, 2024 from the Guatemala's Ministry of Public Health and Social Assistance database. Additional age-stratified data for individuals under 18 years of age were extracted from the national dengue surveillance databases maintained by the Ministry of Public Health of Guatemala for 2019, 2023 and 2024. Results: The dengue cases increased significantly from 9357 in 2013 to 117,942 by October 15, 2024, with a notable rise in severe cases and associated mortality. Spatial dynamics also shifted, with the epicenter moving from Huehuetenango in 2019 to central Guatemala in 2024. Children aged 5-9 years were disproportionately affected, with hospitalization rates and case fatalities increasing significantly. Conclusions: These findings underscore a critical public health crisis, necessitating enhanced surveillance and year-round vector control to mitigate the growing dengue threat in Guatemala.

Indexed as

DengueGuatemalaTemporal dynamics

Identifiers

PMID40520254
PMCPMC12167072

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.