Evidence map›Paper›PMID 40520218›Full record

ReviewFrontiers in digital health2025

Artificial intelligence in clinical decision support and the prediction of adverse events.

S P Oei, T H G F Bakkes, M Mischi, R A Bouwman, R J G van Sloun, S Turco

Abstract readReview
In one paragraph

Review in Frontiers in digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S P Oei *Biomedical Diagnostics Lab, Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
T H G F Bakkes *Biomedical Diagnostics Lab, Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
M MischiBiomedical Diagnostics Lab, Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
R A BouwmanBiomedical Diagnostics Lab, Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
R J G van SlounBiomedical Diagnostics Lab, Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
S TurcoBiomedical Diagnostics Lab, Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review focuses on integrating artificial intelligence (AI) into healthcare, particularly for predicting adverse events, which holds potential in clinical decision support (CDS) but also presents significant challenges. Biases in data acquisition, such as population shifts and data scarcity, threaten the generalizability of AI-based CDS algorithms across different healthcare centers. Techniques like resampling and data augmentation are crucial for addressing biases, along with external validation to mitigate population bias. Moreover, biases can emerge during AI training, leading to underfitting or overfitting, necessitating regularization techniques for balancing model complexity and generalizability. The lack of interpretability in AI models poses trust and transparency issues, advocating for transparent algorithms and requiring rigorous testing on specific hospital populations before implementation. Additionally, emphasizing human judgment alongside AI integration is essential to mitigate the risks of deskilling healthcare practitioners. Ongoing evaluation processes and adjustments to regulatory frameworks are crucial for ensuring the ethical, safe, and effective use of AI in CDS, highlighting the need for meticulous attention to data quality, preprocessing, model training, interpretability, and ethical considerations.

Indexed as

artificial intelligenceclinical decision supportclinical translationdeskillinginterpretable AItrustworthy AI

Identifiers

PMID40520218
PMCPMC12162700

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.