ArticleEnvironmental science & technology letters2025
Retrospective Wastewater Tracking of Measles Outbreak in Western Switzerland in Winter 2024.
Article in Environmental science & technology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Wastewater Surveillance to Track Resurgent Measles Outbreak, Ontario, Canada, 2025.Emerging infectious diseases · 2026Article
- Toward a quality-managed operational architecture for wastewater surveillance of zoonotic and emerging pathogens.Applied and environmental microbiology · 2026Review
- Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak - Colorado, August 2025.MMWR. Morbidity and mortality weekly report · 2026Article
- Spatially Informed Wastewater Differentiation among Locations during an Ongoing Measles Outbreak in Texas, USA.ACS environmental Au · 2025Article
- A targeted tiled amplicon sequencing approach for clade and subclade level differentiation of monkeypox virus from wastewater.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measles outbreaks remain a significant public health challenge, despite high vaccination coverage in many regions. Wastewater-based surveillance (WBS) offers a noninvasive and community-level approach to monitoring the circulation of pathogens, including the measles virus. Here, we retrospectively applied a duplex digital PCR assay to distinguish between wild-type and vaccine strains of the measles virus in wastewater samples available from an existing national WBS program. Samples originated from the wastewater treatment plant serving the Lausanne city catchment area, where an outbreak occurred before spreading to the broader Canton Vaud region. Despite high vaccination rates, viral loads of the measles wild type were detected during the first transmission event involving 21 cases identified within a week. However, viral loads were no longer detectable after the initial 21 cases, despite an additional 30 cases reported in the following 3 weeks, possibly due to lower incidence rate or location outside the catchment. Measles vaccine strain was not detected during the outbreak. Our results demonstrate the complementarity of WBS with clinical surveillance and suggest its potential as an early warning system for measles and other vaccine-preventable diseases. Further improvements in the assay sensitivity and integration with epidemiological data could enhance the utility of WBS for outbreak detection and control.
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