Evidence map›Paper›PMID 40520055›Full record

ArticleScientific African2025

MCMC-Driven mathematical modeling of the impact of HPV vaccine uptake in reducing cervical cancer.

Sylas Oswald, Eunice Mureithi, Berge Tsanou, Michael Chapwanya, Kijakazi Mashoto, Crispin Kahesa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific African, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sylas OswaldDepartment of Mathematics, University of Dar-es-Salaam, P.O Box 35062, Dar-es-salaam, Tanzania.
Eunice MureithiDepartment of Mathematics, University of Dar-es-Salaam, P.O Box 35062, Dar-es-salaam, Tanzania.
Berge TsanouDepartment of Mathematics & Computer Science, University of Dschang, Cameroon.
Michael ChapwanyaDepartment of Mathematics & Applied Mathematics, University of Pretoria, South Africa.
Kijakazi MashotoNational Institute for Medical Research, Headquarters: Dar Es Salaam (NIMR), Tanzania.
Crispin KahesaNational Institute for Medical Research, Headquarters: Dar Es Salaam (NIMR), Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Papillomavirus (HPV) is a group of contagious viruses primarily transmitted through sexual contact and is a major cause of severe health issues, including cervical cancer. In Sub-Saharan Africa, including Tanzania, cervical cancer is the leading cause of cancer-related deaths among women of all ages. In 2022, there were 125,699 new cases and 80,614 deaths, making cervical cancer the second most common cancer. Of these, Tanzania recorded 10,868 cases and 6,832 deaths. To reduce the number of girls and female affected by HPV infections, particularly those vulnerable to cervical cancer, we have developed and analyzed a mathematical model for HPV transmission dynamics that incorporates vaccination. The analysis demonstrates the presence of both HPV-free and endemic equilibrium states. By applying the Graph Theoretic method, the reproduction number

Indexed as

CIN1,2,3DigraphHerd immunityMarkov chainMCMC ranMean posteriorParameter identifiabilitySelf-loopTrivial node

Identifiers

PMID40520055
PMCPMC12166132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.