Time delays in emergency stroke care in a low-resource referral hospital in Ghana.

Background: Patients in sub-Saharan Africa face significant delays in receiving appropriate stroke care, which negatively impacts outcomes. This study aimed to quantify the time delays in acute stroke care at the Komfo Anokye Teaching Hospital (KATH) and determine the effect on mortality. Methods: This was a secondary analysis of prospectively collected data on patients ≥ 18 years with Computed Tomography (CT) scan-confirmed stroke treated at KATH's adult emergency department (ED) from November 2021 to March 2022. Patients were initially enrolled in a pilot stroke registry by trained research assistants, who documented relevant time points in their care. Patient outcome (dead or alive) was determined at time of hospital discharge and three months post-discharge. Data was analyzed using STATA™ version 16. The median times from stroke onset to ED arrival, physician evaluation, CT scan imaging, and treatment were measured and the relationship with mortality determined. Results: Eighty-six patients with confirmed stroke were analyzed, comprising 40 males and 46 females. Ages ranged between 29 and 86 years, with mean of 57.4 years (SD 14.3). The median time from stroke onset to arrival at KATH ED was 35.3 h (IQR: 12.3-79.5). The median time from ED arrival to first physician evaluation was 1.3 h (IQR: 0.5-2.6); to CT imaging was 14.1 h (IQR: 4.3-40.8); and to antiplatelet treatment (for ischemic stroke) was 31.1 h (IQR: 16.1-42.5). The cumulative mortality rates at three months post-discharge were 8.7 % for patients who arrived at KATH's ED within 4 h of symptom onset, 43.5 % for those arriving between 4 and 24 h, and 47.8 % for those arriving after 24 h, Conclusion: Significant delays occurred in all stages of stroke care at KATH's ED. Improving stroke education and implementing contextually appropriate stroke codes can enable early patient presentations, improve intervention times, and reduce mortality rates.