Evidence map›Paper›PMID 40519991›Full record

ArticlePNAS nexus2025

One-hour postload glucose levels predict mortality from cardiovascular diseases and malignant neoplasms in healthy subjects.

Daiki Sato, Junta Imai, Michihiro Satoh, Yohei Kawana, Hiroto Sugawara, Akira Endo, Masato Kohata, Junro Seike, Hiroshi Komamura, Toshihiro Sato and 17 more

Abstract read
In one paragraph

Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Daiki SatoDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Junta ImaiDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.ORCID https://orcid.org/0000-0003-4636-5905
Michihiro SatohDivision of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 983-8536, Japan.ORCID https://orcid.org/0000-0003-1688-1239
Yohei KawanaDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Hiroto SugawaraDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Akira EndoDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Masato KohataDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Junro SeikeDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Hiroshi KomamuraDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.ORCID https://orcid.org/0009-0004-1780-7289
Toshihiro SatoDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.ORCID https://orcid.org/0000-0001-8033-8340
Shinichiro HosakaDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Yoichiro AsaiDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Shinjiro KodamaDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Kei TakahashiDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.ORCID https://orcid.org/0000-0001-9167-2336
Keizo KanekoDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.ORCID https://orcid.org/0000-0003-1612-7957
Yukako TatsumiDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo 173-8605, Japan.ORCID https://orcid.org/0000-0002-4933-3514
Takahisa MurakamiDivision of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 983-8536, Japan.
Takuo HiroseDivision of Integrative Renal Replacement Therapy, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 983-8536, Japan.ORCID https://orcid.org/0000-0002-8761-3779
Azusa HaraLaboratory of Social Pharmacy and Epidemiology, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Ryusuke InoueDepartment of Medical Information Technology Center, Tohoku University Hospital, Sendai, Miyagi 980-8574, Japan.
Kei AsayamaDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo 173-8605, Japan.ORCID https://orcid.org/0000-0003-3365-0547
Hirohito MetokiDivision of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 983-8536, Japan.
Atsushi HozawaDepartment of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi 980-0872, Japan.
Masahiro KikuyaDepartment of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi 980-0872, Japan.ORCID https://orcid.org/0000-0002-3080-6107
Yutaka ImaiTohoku Institute for Management of Blood Pressure, Hanamaki, Iwate 028-3203, Japan.
Takayoshi OhkuboDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo 173-8605, Japan.ORCID https://orcid.org/0000-0002-3283-8196
Hideki KatagiriDepartment of Diabetes, Metabolism and Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about biological markers, at levels within their normal ranges which might predict future mortality. We aimed at identifying possible predictors of future death in participants before pathological conditions manifest. We analyzed data from a population-based prospective cohort study (the Ohasama study), comprised of 993 participants who underwent 75-g oral glucose tolerance tests (OGTTs). We collected blood parameters, including those measured during OGTTs, and divided the study population into two groups based on the median value of each parameter, followed by analyses of mortality during follow-up in both groups. In addition, we extracted subjects with normal glucose tolerance (NGT) (

Indexed as

1-h postload plasma glucosecardiovascular diseasesmalignant neoplasmsmortalityoral glucose tolerance tests

Identifiers

PMID40519991
PMCPMC12163372

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.