Evidence map›Paper›PMID 40519938›Full record

ArticleFrontiers in immunology2025

Transcriptional profiling reveals

Jinshui Tan, Zhengxin Wu, Yuankun Liu, Wei Wang, Wenjuan Qin, Guangchao Pan, Yubo Xiong, Jingsong Ma, Jiabao Zhao, Huiwen Zhou and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Integrated virulence-resistance profiling ofFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jinshui Tan *Department of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Zhengxin Wu *Department of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Yuankun Liu *Department of Gastroenterology, The National Key Clinical Specialty, Clinical Research Center for Gut Microbiota and Digestive Diseases of Fujian Province, Key Laboratory for Intestinal Microbiome and Human Health of Xiamen, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Wei Wang *Department of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Wenjuan QinDepartment of Radiation Oncology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Guangchao PanDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Yubo XiongDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Jingsong MaDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Jiabao ZhaoDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Huiwen ZhouDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
ZhengJin LiuDepartment of Pathology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Haijie LuDepartment of Radiation Oncology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Huiqin ZhuoDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Xuehui HongDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Employing transcriptional bioinformatics, we computed a Results: ACSM5 and HSPB2 were identified as correlates of Conclusion: The HPI, reflecting newly identified and complementary biomarkers, correlated with the TME and could accurately project chemoresistance and an altered immune cell distribution in GC patients, thus providing clinical guidance on therapeutic interventions.

Indexed as

Drug Resistance, NeoplasmHelicobacter InfectionsHelicobacter pyloriStomach NeoplasmsAntineoplastic AgentsBiomarkers, TumorGene Expression ProfilingGene Expression Regulation, NeoplasticHeat-Shock ProteinsHumansPrognosisTumor MicroenvironmentAntineoplastic AgentsBiomarkers, TumorHeat-Shock ProteinsACSM5eosinophilsgastric cancerH. pyloriHspB2tumor microenvironment

Identifiers

PMID40519938
PMCPMC12162319

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.