Evidence map›Paper›PMID 40519841›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2025

Prospective Evaluation of Artificial Intelligence Imaging Support Software for Acute Ischemic Stroke in the Mayo Clinic Telestroke Network.

Brett H Smith, Jackson G Wolfe, Alvina Karam, Bart M Demarkschalk, Courtney M Hrdlicka, Deena M Nasr, Felix E Chukwudelunzu, Charisse A Nord, Emily A Pahl, Claire Fernandez and 5 more

Abstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Brett H SmithDepartment of Neurology, Mayo Clinic, Jacksonville, FL.
Jackson G WolfeDepartment of Neurology, Mayo Clinic, Jacksonville, FL.
Alvina KaramDepartment of Neurology, Mayo Clinic, Jacksonville, FL.
Bart M DemarkschalkDepartment of Neurology, Mayo Clinic, Pheonix, AZ.
Courtney M HrdlickaCenter for Digital Health, Mayo Clinic College of Medicine and Science, Pheonix, AZ.
Deena M NasrCenter for Digital Health, Mayo Clinic College of Medicine and Science, Pheonix, AZ.
Felix E ChukwudelunzuDepartment of Neurology, Mayo Clinic Health System, Eau Claire, WI.
Charisse A NordCenter for Digital Health, Mayo Clinic College of Medicine and Science, Pheonix, AZ.
Emily A PahlCenter for Digital Health, Mayo Clinic College of Medicine and Science, Pheonix, AZ.
Claire FernandezBrainomix Limited, Oxford, United Kingdom.
Sam WoodBrainomix Limited, Oxford, United Kingdom.
Zoe Vj WoodheadBrainomix Limited, Oxford, United Kingdom.
Davide CaroneBrainomix Limited, Oxford, United Kingdom.
George HarstonBrainomix Limited, Oxford, United Kingdom.
Stephen W EnglishDepartment of Neurology, Mayo Clinic, Jacksonville, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the real-world impact of artificial intelligence-driven decision support imaging software for patients with acute ischemic stroke in a mature telestroke network in the United States. Patients and Methods: We conducted a prospective evaluation of stroke imaging support software in a robust, predominantly rural telestroke network (17 sites in Minnesota and Wisconsin). Data was collected from all patients who underwent video telestroke evaluation in a 3-month preimplementation period before installation of the software (from February 10, 2024 to May 9, 2024) and a 3-month postimplementation period while the software was in use (from May 10, 2024 to August 9, 2024). The preimplementation and postimplementation cohorts were directly compared (no control group included). Primary outcome measures were treatment rates and time to treatment (both treatment decision and delivery) for intravenous thrombolysis (IVT) and endovascular therapy (EVT); secondary outcomes included transfer rates, transfer times, and end user survey results. Results: Total of 444 telestroke cases were included in the preimplementation period, and 463 in the postimplementation period. Comparing preimplementation and postimplementation periods, the rate of IVT treatment delivery rose from 26.6% to 35.0% of potentially eligible patients ( Conclusion: This study reported a nonsignificant increase in treatment rates and a decrease in time to treatment decisions. Future trials with larger sample sizes are needed to validate the real-world benefits of decision support software for acute ischemic stroke in an established telestroke network.

Identifiers

PMID40519841
PMCPMC12163383

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.