Evidence map›Paper›PMID 40519790›Full record

ArticleRadiology case reports2025

Pneumonitis secondary to intravesical Bacillus-Calmette-Guérin (BCG) immunotherapy.

Komeil Alattar, Sagar Dodhia, Michael Levi

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Komeil AlattarDartford and Gravesham NHS Trust, Kent, United Kingdom.
Sagar DodhiaDartford and Gravesham NHS Trust, Kent, United Kingdom.
Michael LeviDartford and Gravesham NHS Trust, Kent, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intra vesical Bacillus Calmette-Guérin (BCG) instillation therapy is a well-established treatment for superficial bladder cancer, though it can occasionally lead to rare systemic complications. We report the case of a man in his early 80s who developed acute onset dyspnoea after receiving BCG therapy. Clinical evaluation supported by pathology and multi-modal imaging including X-rays, CTs and PET scans led to a diagnosis of BCG-induced pneumonitis, a rare but serious complication. The exact underlying mechanism is still not fully understood and thus no standardized treatment protocol exists. Success has been reported in the literature with the use of anti-tuberculous drugs in combination with steroids. Our patient was successfully treated with anti-tuberculous medication only, for 4 months. This case highlights the importance of maintaining awareness for systemic BCG findings in patients undergoing intra vesical BCG instillations.

Indexed as

Bacillus-Calmette-GuérinBCG immunotherapyBCG pneumonitisHypersensitivity pneumonitisInterstitial pneumonitisMycobacterium bovis

Identifiers

PMID40519790
PMCPMC12167076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.