Evidence map›Paper›PMID 40519744›Full record

ArticleTranslational pediatrics2025

Changes in airway resistance and its correlation with disease severity in children with

Jiayi Xue, Yinghong Fan, Ronghua Luo, Yaping Duan, Tao Ai, Li Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiayi XueDepartment of Pediatric Respiratory Medicine, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.ORCID https://orcid.org/0009-0005-9789-1130
Yinghong FanDepartment of Pediatric Respiratory Medicine, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Ronghua LuoDepartment of Pediatric Respiratory Medicine, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Yaping DuanDepartment of Pediatric Respiratory Medicine, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Tao Ai *Department of Pediatric Respiratory Medicine, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Li Wang *Department of Pediatric Respiratory Medicine, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: A total of 96 children with MPP, admitted to Chengdu Women's and Children's Center Hospital from December 2022 to December 2023, were recruited for the study. The children were allocated to the mild MPP (MMPP) group (n=39) and the SMPP group (n=57) based on disease severity. Indices derived from impulse oscillometry (IOS) were compared, and receiver operating characteristic (ROC) curves were generated to assess the predictive value of various indicators for SMPP. Results: The results revealed significant increases in respiratory resistance at 5 Hz (R5), respiratory resistance at 20 Hz (R20), reactance at 5 Hz (X5), and resonant frequency (Fres) in the SMPP group compared to the MMPP group (P<0.05). Compared to the children in the MMPP group, those in the SMPP group had a significantly longer hospital length of stay, and a higher proportion were admitted to the intensive care unit (ICU) and received mechanical ventilation (P<0.05). A positive correlation was found between MPP severity and R5, R20, X5, Fres, and hospital length of stay, of which R5 showed the strongest correlation. The ROC curve analysis indicated that R5 was the most effective predictor of SMPP, with an area under the curve (AUC) indicating good predictive ability [R5 > R20 > hospital length of stay > X5 (0.70)]. R5 had the highest predictive value for SMPP, with a sensitivity of 82.46%, a specificity of 87.18%, a cut-off value of 123.80%, a positive predictive value (PPV) of 90.38%, and a negative predictive value (NPV) of 77.27%. Conclusions: The airway resistance of the children with SMPP was significantly higher than that of the children with MMPP. The primary increase was observed in small airway resistance, which might be accompanied by an increase in large airway resistance, along with a decrease in lung compliance. R5, R20, and X5 were found to be correlated with the severity of MPP, indicating that IOS is a valuable tool for assessing MPP severity.

Indexed as

airway resistancechildrenimpulse oscillometry (IOS)Mycoplasma pneumoniae pneumonia (MMP)

Identifiers

PMID40519744
PMCPMC12163775

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.