ArticleTranslational pediatrics2025
Fluid management during pediatric lung transplantation: a single-center experience.
Article in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Anesthetic management for double lung transplantation in an 8-year-old male with extreme malnutrition (BMI 11.4 kg/mTranslational pediatrics · 2026Article
- Lung transplantation in 2025: a narrative review of progress, challenges, and the road ahead.Journal of thoracic disease · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The impact of intraoperative fluid balance on postoperative outcomes in pediatric lung transplantation (LTx) has not been conclusively established. This study aimed to investigate the effect of fluid balance on postoperative outcomes in pediatric LTx, while also sharing insights from our clinical experiences in fluid management. Methods: We reviewed the medical records of children who underwent LTx from July 2019 to August 2023. Intraoperative data, fluid management strategies, and postoperative outcomes were recorded. Fluid overload (FO) was defined as an intraoperative fluid balance ≥10%. The patients were categorized into two groups: FO and non-FO. Differences in the incidence of primary graft dysfunction (PGD) and other outcomes were compared between these groups. Results: A total of 20 children were included in the study, with 12 in the FO group and 8 in the non-FO group. The analysis revealed no significant differences between the two groups regarding postoperative grade 3 PGD (P=0.35), acute kidney injury (AKI) within 48 hours after surgery (P=0.67), duration of postoperative mechanical ventilation (P=0.05), and duration of ICU stay (P=0.73). Although red blood cell (RBC) (P=0.13), fresh frozen plasma (FFP) (P=0.16), crystalloid (P=0.61) and total intake (P=0.23) were higher in the PGD group compared to the non-PGD group, these differences were not statistically significant. Conclusions: The current evidence is insufficient to support the hypothesis that a non-FO approach within a restrictive fluid strategy can reduce the risk of adverse outcomes following pediatric LTx. However, this does not imply that an FO strategy should be advocated. Further high-quality clinical studies are necessary to validate these findings.
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Registered trials
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