Evidence map›Paper›PMID 40519723›Full record

ArticleTranslational pediatrics2025

Trends in short-term outcomes of very low birth weight infants from a single center in Shanghai from 2013 to 2023.

Ling Zhao, Wan Tang, Pu Xu, Ziming Wang, Jiayu Zhou, Yingying Jiang, Zhuoyu Zhao, Rong Zhang, Jin Wang, Laishuan Wang

Abstract read
In one paragraph

Article in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ling ZhaoNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.ORCID https://orcid.org/0009-0002-9726-7141
Wan TangNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.
Pu XuDepartment of Neonatology, Children's Hospital of Capital Institute of Pediatrics/Peking Union Medical College/Chinese Academy of Medical Sciences, Beijing, China.
Ziming WangNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.
Jiayu ZhouNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.
Yingying JiangNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.
Zhuoyu ZhaoNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.
Rong ZhangNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.
Jin WangNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.
Laishuan WangNeonatal Medical Center, Children's Hospital of Fudan University/National Children's Medical Center/National Health Commission Key Laboratory of Neonatal Diseases, Shanghai, China.ORCID https://orcid.org/0000-0003-0527-8186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Very low birth weight infants (VLBWI) are vulnerable to serious complications. We aim to describe the short-term outcomes of VLBWI in a single center during 2013-2023, providing the basis for clinical disease management. Methods: A retrospective study of VLBWI admitted to a tertiary neonatal intensive care unit (NICU) between 1 January 2013 and 31 December 2023 was conducted to analyze trends of mortality and major morbidities over the 11-year period. Infants were divided into two subgroups according to birth weight (BW): <1,000 and 1,000-1,500 g. Major morbidities were defined as bronchopulmonary dysplasia (BPD), late onset sepsis (LOS), intraventricular hemorrhage (IVH) ≥ grade 3, necrotizing enterocolitis (NEC) ≥ stage 2, retinopathy of prematurity (ROP) ≥ stage 3 or needed treatment, and periventricular leukomalacia (PVL). Results: A total of 2,475 VLBWI were enrolled from 2013 to 2023. Analysis showed that the overall trend of mortality, LOS, NEC, IVH and PVL decreased, but BPD and ROP increased during the 11 years. Except for ROP, which exhibited a consistent increasing trend, other outcomes have a significant inflection point. Mortality, LOS, NEC, IVH and PVL kept steady initially, but decreased quickly around 2017. BPD was stable from 2013 to 2016, after which it increased dramatically. Most trends in the two subgroups by BW were similar to the patterns in the overall infants. Conclusions: Mortality and most morbidities in VLBWI decreased from 2013 to 2023, with the exception of BPD and ROP. Continuous research and quality improvement (QI) efforts should be made to further improve the outcomes of VLBWI, especially for BPD and ROP.

Indexed as

morbiditymortalityprematureTrendsvery low birth weights (VLBW)

Identifiers

PMID40519723
PMCPMC12163821

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.