Evidence map›Paper›PMID 40519584›Full record

ArticleNano research2024

Materials Advancements for the Safety and Patency of Implantable Cardiovascular Devices.

Zulmari Silva Pedraza, Bo Liu, Xudong Wang

Abstract read
In one paragraph

Article in Nano research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zulmari Silva PedrazaDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Bo LiuDepartments of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, United States.
Xudong WangDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.

Funding

Nanogenerator-Driven Self-Sustainable Power Source for Intracardiac PacemakersR01HL157077 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, XUDONG · 2021 to 2024
$2.7M
NHLBI NIH HHS R01 HL157077
6 · The paper itself

Abstract

Implantable cardiovascular devices have revolutionized the management of cardiovascular diseases, significantly enhancing patients' quality of life. With the increasing demand of cardiac implantable electronic devices, the imperative for novel device development is evident. This review article first elaborates the mechanisms underlying foreign body response and infection, elucidating the complex interplay between implanted constructs and host tissues. The discussion then focuses on current advancements in materials science and engineering aimed at mitigating these challenges. Material innovations, such as drug-eluting materials, surface modifications, and biomimetic materials, are explored as strategies to modulate these responses and to prevent fibrotic or thrombotic complications and infection. Finally, future directions in materials development for implantable cardiovascular devices are introduced. By addressing safety and patency concerns through innovative material strategies, this article aims to guide the research and development of advanced materials for both current and future cardiovascular implantable devices, ultimately improving patient outcomes and advancing cardiovascular disease treatment.

Indexed as

BiomaterialsCardiovascular diseasesImplantable devicesImplantable materials

Identifiers

PMID40519584
PMCPMC12162047

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.