Evidence map›Paper›PMID 40519555›Full record

ArticleFrontiers in pediatrics2025

Survival assessment in extremely preterm neonates in a middle-income setting.

Maria J Rodriguez-Sibaja, Olivo Herrera-Ortega, Mario I Lumbreras-Marquez, Deneb Morales-Barquet, Sandra Acevedo-Gallegos, Yazmin Copado-Mendoza, Dulce M Camarena-Cabrera, Juan M Gallardo-Gaona

Abstract read
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Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria J Rodriguez-SibajaMaternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Olivo Herrera-OrtegaMaternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Mario I Lumbreras-MarquezMaternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Deneb Morales-BarquetNeonatology Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Sandra Acevedo-GallegosMaternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Yazmin Copado-MendozaMaternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Dulce M Camarena-CabreraMaternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Juan M Gallardo-GaonaMaternal-Fetal Medicine Division, Instituto Nacional de Perinatologia, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Globally, an estimated 15.1 million preterm neonates are born annually, with 1% classified as extremely preterm (i.e., <28.0 weeks of gestation). The survival and outcomes of this vulnerable population are influenced by multiple factors, particularly gestational age, birth weight, and available medical resources. This study aimed to describe the hospital discharge survival of extremely preterm infants born in a middle-income setting. As a secondary objective, we assessed the neonatal morbidity associated with this group. Material and methods: In this cross-sectional study of singleton pregnancies Results: There were no live births between 22.0 and 23.6 weeks of gestation. Overall mortality decreased with increasing gestational age, from 100% (22/22) at <24.0 weeks of gestation to 87% (14/16), 42% (16/38), and 21% (11/52) at a gestational age of 25, 26, and 27 weeks, respectively. The survival rate to NICU discharge among extremely preterm infants was 49% (65/132), 67% (65/97), and 69% (65/93), depending on whether survival was calculated based on all births, all live births, or NICU admissions, respectively. None of the neonates born before 24.6 weeks of gestation survived to discharge. Notably, 97.0% of NICU survivors were diagnosed with major morbidity. Conclusion: The survival rate at NICU discharge exceeds 50% from 26 weeks onwards in a middle-income setting. Importantly, survival rates varied significantly depending on the denominator used, highlighting the need to carefully select inclusion criteria in neonatal survival analyses. Notably, survival after extremely preterm birth was associated with significant morbidity.

Indexed as

extreme prematuritygrey zoneneonatal survivalperinatal mortalityviability limit

Identifiers

PMID40519555
PMCPMC12162604

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.